eF-site ID 2ast-B PDB Code 2ast Chain B click to enlarge Title Crystal structure of Skp1-Skp2-Cks1 in complex with a p27 peptide Classification LIGASE/LIGASE INHIBITOR Compound S-phase kinase-associated protein 1A Source Homo sapiens (Human) (CDN1B_HUMAN) Sequence B:  VSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDE SLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPL AEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLE GLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSS CSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYR KNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQL NYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDG TLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKC RLTLQ Description Functional site 1) chain B residue 2169 type sequence F description BINDING SITE FOR RESIDUE BEN C 1001 source : AC1 2) chain B residue 2192 type sequence V description BINDING SITE FOR RESIDUE BEN C 1001 source : AC1 3) chain B residue 2227 type sequence A description BINDING SITE FOR RESIDUE BEN B 1002 source : AC2 4) chain B residue 2230 type sequence S description BINDING SITE FOR RESIDUE BEN B 1002 source : AC2 5) chain B residue 2254 type sequence S description BINDING SITE FOR RESIDUE BEN B 1002 source : AC2 6) chain B residue 2294 type sequence R description BINDING SITE FOR CHAIN D OF CYCLIN-DEPENDENT KINASE INHIBITOR 1B source : AC3 7) chain B residue 2346 type sequence Y description BINDING SITE FOR CHAIN D OF CYCLIN-DEPENDENT KINASE INHIBITOR 1B source : AC3 8) chain B residue 2347 type sequence D description BINDING SITE FOR CHAIN D OF CYCLIN-DEPENDENT KINASE INHIBITOR 1B source : AC3

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