eF-site ID 2aob-D PDB Code 2aob Chain D click to enlarge Title Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain Classification TRANSFERASE Compound Growth factor receptor-bound protein 2 Source Homo sapiens (Human) (GRB2_HUMAN) Sequence D:  PWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLS VKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRST SVSRNQQIFLRDI Description Functional site 1) chain D residue 142 type sequence R description BINDING SITE FOR RESIDUE S1S A 1201 source : AC1 2) chain D residue 109 type sequence K description BINDING SITE FOR RESIDUE S1S A 1401 source : AC3 3) chain D residue 111 type sequence L description BINDING SITE FOR RESIDUE S1S A 1401 source : AC3 4) chain D residue 112 type sequence R description BINDING SITE FOR RESIDUE S1S A 1501 source : AC4 5) chain D residue 67 type sequence R description BINDING SITE FOR RESIDUE S1S D 2301 source : AC8 6) chain D residue 86 type sequence R description BINDING SITE FOR RESIDUE S1S D 2301 source : AC8 7) chain D residue 96 type sequence S description BINDING SITE FOR RESIDUE S1S D 2301 source : AC8 8) chain D residue 106 type sequence Q description BINDING SITE FOR RESIDUE S1S D 2301 source : AC8 9) chain D residue 107 type sequence H description BINDING SITE FOR RESIDUE S1S D 2301 source : AC8 10) chain D residue 108 type sequence F description BINDING SITE FOR RESIDUE S1S D 2301 source : AC8 11) chain D residue 109 type sequence K description BINDING SITE FOR RESIDUE S1S D 2301 source : AC8 12) chain D residue 111 type sequence L description BINDING SITE FOR RESIDUE S1S D 2301 source : AC8 13) chain D residue 120 type sequence L description BINDING SITE FOR RESIDUE S1S D 2301 source : AC8 14) chain D residue 121 type sequence W description BINDING SITE FOR RESIDUE S1S D 2301 source : AC8 15) chain D residue 121 type sequence W description BINDING SITE FOR RESIDUE S1S C 2401 source : AC9 16) chain D residue 122 type sequence V description BINDING SITE FOR RESIDUE S1S C 2401 source : AC9 17) chain D residue 124 type sequence K description BINDING SITE FOR RESIDUE S1S C 2401 source : AC9 18) chain D residue 125 type sequence F description BINDING SITE FOR RESIDUE S1S C 2401 source : AC9 19) chain D residue 130 type sequence E description BINDING SITE FOR RESIDUE S1S C 2401 source : AC9 20) chain D residue 126 type sequence N description BINDING SITE FOR RESIDUE S1S C 2501 source : BC1 21) chain D residue 127 type sequence S description BINDING SITE FOR RESIDUE S1S C 2601 source : BC2 22) chain D residue 128 type sequence L description BINDING SITE FOR RESIDUE S1S C 2601 source : BC2 23) chain D residue 126 type sequence N description BINDING SITE FOR RESIDUE S1S D 2701 source : BC3 24) chain D residue 127 type sequence S description BINDING SITE FOR RESIDUE S1S D 2701 source : BC3 25) chain D residue 109 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI1

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