eF-site ID 2aob-B PDB Code 2aob Chain B click to enlarge Title Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain Classification TRANSFERASE Compound Growth factor receptor-bound protein 2 Source Homo sapiens (Human) (GRB2_HUMAN) Sequence B:  PWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLS VKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRST SVSRNQQIFLRDI Description Functional site 1) chain B residue 67 type sequence R description BINDING SITE FOR RESIDUE S1S B 1301 source : AC2 2) chain B residue 86 type sequence R description BINDING SITE FOR RESIDUE S1S B 1301 source : AC2 3) chain B residue 96 type sequence S description BINDING SITE FOR RESIDUE S1S B 1301 source : AC2 4) chain B residue 106 type sequence Q description BINDING SITE FOR RESIDUE S1S B 1301 source : AC2 5) chain B residue 107 type sequence H description BINDING SITE FOR RESIDUE S1S B 1301 source : AC2 6) chain B residue 108 type sequence F description BINDING SITE FOR RESIDUE S1S B 1301 source : AC2 7) chain B residue 109 type sequence K description BINDING SITE FOR RESIDUE S1S B 1301 source : AC2 8) chain B residue 111 type sequence L description BINDING SITE FOR RESIDUE S1S B 1301 source : AC2 9) chain B residue 120 type sequence L description BINDING SITE FOR RESIDUE S1S B 1301 source : AC2 10) chain B residue 121 type sequence W description BINDING SITE FOR RESIDUE S1S B 1301 source : AC2 11) chain B residue 121 type sequence W description BINDING SITE FOR RESIDUE S1S A 1401 source : AC3 12) chain B residue 122 type sequence V description BINDING SITE FOR RESIDUE S1S A 1401 source : AC3 13) chain B residue 124 type sequence K description BINDING SITE FOR RESIDUE S1S A 1401 source : AC3 14) chain B residue 125 type sequence F description BINDING SITE FOR RESIDUE S1S A 1401 source : AC3 15) chain B residue 130 type sequence E description BINDING SITE FOR RESIDUE S1S A 1401 source : AC3 16) chain B residue 126 type sequence N description BINDING SITE FOR RESIDUE S1S A 1501 source : AC4 17) chain B residue 127 type sequence S description BINDING SITE FOR RESIDUE S1S A 1601 source : AC5 18) chain B residue 128 type sequence L description BINDING SITE FOR RESIDUE S1S A 1601 source : AC5 19) chain B residue 126 type sequence N description BINDING SITE FOR RESIDUE S1S A 1701 source : AC6 20) chain B residue 127 type sequence S description BINDING SITE FOR RESIDUE S1S A 1701 source : AC6 21) chain B residue 142 type sequence R description BINDING SITE FOR RESIDUE S1S C 2201 source : AC7 22) chain B residue 109 type sequence K description BINDING SITE FOR RESIDUE S1S C 2401 source : AC9 23) chain B residue 111 type sequence L description BINDING SITE FOR RESIDUE S1S C 2401 source : AC9 24) chain B residue 112 type sequence R description BINDING SITE FOR RESIDUE S1S C 2501 source : BC1 25) chain B residue 109 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI1

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