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eF-site ID
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2ajq-A |
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PDB Code
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2ajq |
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Chain
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A |
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click to enlarge
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Title
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Structure of replicative DNA polymerase provides insigts into the mechanisms for processivity, frameshifting and editing |
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Classification
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TRANSFERASE,TRANSCRIPTION/DNA |
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Compound
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DNA Primer |
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Source
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Enterobacteria phage T7 (Bacteriophage T7) (2AJQ) |
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Sequence
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A: |
MIVSAIAANALLESVTKFHCGVIYDYSTAEYVSYRPSDFG
AYLDALEAEVARGGLIVFHNGHKYDVPALTKLAKLQLNRE
FHLPRENCIDTLVLSRLIHSNLKDTDMGLLRSGKLPGKRF
GSHALEAWGYRLGEMKGEYKDDFKRMLEEQGEEYVDGMEW
WNFNEEMMDYNVQDVVVTKALLEKLLSDKHYFPPEIDFTD
VGYTTFWSESLEAVDIEHRAAWLLAKQERNGFPFDTKAIE
ELYVELAARRSELLRKLTETFGSWYQPKGGTEMFCHPRTG
KPLPKYPRIKTPKVGGIFKKPKNKAQREGREPCELDTREY
VAGAPYTPVEHVVFNPSSRDHIQKKLQEAGWVPTKYTDKG
APVVDDEVLEGVRVDDPEKQAAIDLIKEYLMIQKRIGQSA
EGDKAWLRYVAEDGKIHGSVNPNGAVTGRATHAFPNLAQI
PGVRSPYGEQCRAAFGAEHHLDGITGKPWVQAGIDASGLE
LRCLAHFMARFDNGEYAHEILNGDIHTKNQIAAELPTRDN
AKTFIYGFLYGAGDEKIGQIVGAGKERGKELKKKFLENTP
AIAALRESIQQTLVESSQWVAGEQQVKWKRRWIKGLDGRK
VHVRSPHAALNTLLQSAGALICKLWIIKTEEMLVEKGLKH
GWDGDFAYMAWVHDEIQVGCRTEEIAQVVIETAQEAMRWV
GDHWNFRCLLDTEGKMGPNWAICH
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Description
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Functional site
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1)
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chain |
A |
| residue |
654 |
| type |
SITE |
| sequence |
D
|
| description |
Deprotonates C-terminal active site Cys
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| source |
Swiss-Prot : SWS_FT_FI2
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2)
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chain |
A |
| residue |
518-537 |
| type |
prosite |
| sequence |
RDNAKTFIYGFLYGAGDEKI
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| description |
DNA_POLYMERASE_A DNA polymerase family A signature. RdnAKtfiYGflYgaGdekI
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| source |
prosite : PS00447
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