eF-site ID 2afg-ABCD PDB Code 2afg Chain A, B, C, D click to enlarge Title 2.0 ANGSTROM X-RAY STRUCTURE OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR Classification GROWTH FACTOR Compound ACIDIC FIBROBLAST GROWTH FACTOR Source (FGF1_HUMAN) Sequence A:  KPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAE SVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERL EENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKA ILFLPLPVS B:  KPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAE SVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERL EENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKA ILFLPLPVS C:  PKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAES VGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLE ENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAI LFLPLPV D:  PKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAES VGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLE ENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAI LFLPLPVS Description Functional site 1) chain A residue 18 type sequence N description BINDING SITE FOR RESIDUE SO4 A 150 source : AC1 2) chain A residue 112 type sequence K description BINDING SITE FOR RESIDUE SO4 A 150 source : AC1 3) chain A residue 113 type sequence K description BINDING SITE FOR RESIDUE SO4 A 150 source : AC1 4) chain A residue 118 type sequence K description BINDING SITE FOR RESIDUE SO4 A 150 source : AC1 5) chain B residue 18 type sequence N description BINDING SITE FOR RESIDUE SO4 B 150 source : AC2 6) chain B residue 112 type sequence K description BINDING SITE FOR RESIDUE SO4 B 150 source : AC2 7) chain B residue 113 type sequence K description BINDING SITE FOR RESIDUE SO4 B 150 source : AC2 8) chain B residue 118 type sequence K description BINDING SITE FOR RESIDUE SO4 B 150 source : AC2 9) chain C residue 18 type sequence N description BINDING SITE FOR RESIDUE SO4 C 150 source : AC3 10) chain C residue 112 type sequence K description BINDING SITE FOR RESIDUE SO4 C 150 source : AC3 11) chain C residue 113 type sequence K description BINDING SITE FOR RESIDUE SO4 C 150 source : AC3 12) chain C residue 118 type sequence K description BINDING SITE FOR RESIDUE SO4 C 150 source : AC3 13) chain D residue 18 type sequence N description BINDING SITE FOR RESIDUE SO4 D 150 source : AC4 14) chain D residue 112 type sequence K description BINDING SITE FOR RESIDUE SO4 D 150 source : AC4 15) chain D residue 113 type sequence K description BINDING SITE FOR RESIDUE SO4 D 150 source : AC4 16) chain D residue 118 type sequence K description BINDING SITE FOR RESIDUE SO4 D 150 source : AC4 17) chain A residue 71-94 type prosite sequence GLLYGSQTPNEECLFLERLEENHY description HBGF_FGF HBGF/FGF family signature. GlLyGsqtpne.EClFlErleenhY source prosite : PS00247 18) chain A residue 18 type BINDING sequence N description BINDING => ECO:0000269|PubMed:11069186, ECO:0000269|PubMed:9655399 source Swiss-Prot : SWS_FT_FI1 19) chain B residue 18 type BINDING sequence N description BINDING => ECO:0000269|PubMed:11069186, ECO:0000269|PubMed:9655399 source Swiss-Prot : SWS_FT_FI1 20) chain C residue 18 type BINDING sequence N description BINDING => ECO:0000269|PubMed:11069186, ECO:0000269|PubMed:9655399 source Swiss-Prot : SWS_FT_FI1 21) chain D residue 18 type BINDING sequence N description BINDING => ECO:0000269|PubMed:11069186, ECO:0000269|PubMed:9655399 source Swiss-Prot : SWS_FT_FI1

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