eF-site ID 2abm-H PDB Code 2abm Chain H click to enlarge Title Crystal Structure of Aquaporin Z Tetramer Reveals both Open and Closed Water-conducting Channels Classification MEMBRANE PROTEIN Compound Aquaporin Z Source (AQPZ_ECOLI) Sequence H:  MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVA LAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKE VVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNG YGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAG FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGW ALEQLWFFWVVPIVGGIIGGLIYRTLL Description Functional site 1) chain H residue 1-8 type TOPO_DOM sequence MFRKLAAE description Cytoplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 2) chain H residue 55-81 type TOPO_DOM sequence GHISGGHFNPAVTIGLWAGGRFPAKEV description Cytoplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 3) chain H residue 152-155 type TOPO_DOM sequence ATDK description Cytoplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 4) chain H residue 9-29 type TRANSMEM sequence CFGTFWLVFGGCGSAVLAAGF description Helical; Name=1 => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 5) chain H residue 30-33 type TOPO_DOM sequence PELG description Periplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI3 6) chain H residue 103-130 type TOPO_DOM sequence ASGKTGFDAAASGFASNGYGEHSPGGYS description Periplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI3 7) chain H residue 177-201 type TOPO_DOM sequence SIPVTNTSVNPARSTAVAIFQGGWA description Periplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI3 8) chain H residue 34-54 type TRANSMEM sequence IGFAGVALAFGLTVLTMAFAV description Helical; Name=2 => ECO:0000255 source Swiss-Prot : SWS_FT_FI4 9) chain H residue 82-102 type TRANSMEM sequence VGYVIAQVVGGIVAAALLYLI description Helical; Name=3 => ECO:0000255 source Swiss-Prot : SWS_FT_FI5 10) chain H residue 131-151 type TRANSMEM sequence MLSALVVELVLSAGFLLVIHG description Helical; Name=4 => ECO:0000255 source Swiss-Prot : SWS_FT_FI6 11) chain H residue 156-176 type TRANSMEM sequence FAPAGFAPIAIGLALTLIHLI description Helical; Name=5 => ECO:0000255 source Swiss-Prot : SWS_FT_FI7 12) chain H residue 202-222 type TRANSMEM sequence LEQLWFFWVVPIVGGIIGGLI description Helical; Name=6 => ECO:0000255 source Swiss-Prot : SWS_FT_FI8 13) chain H residue 20 type SITE sequence C description Involved in tetramerization or stability of the tetramer source Swiss-Prot : SWS_FT_FI9 14) chain H residue 43 type SITE sequence F description Selectivity filter source Swiss-Prot : SWS_FT_FI10 15) chain H residue 174 type SITE sequence H description Selectivity filter source Swiss-Prot : SWS_FT_FI10 16) chain H residue 183 type SITE sequence T description Selectivity filter source Swiss-Prot : SWS_FT_FI10 17) chain H residue 189 type SITE sequence R description Selectivity filter source Swiss-Prot : SWS_FT_FI10

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