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eF-site ID
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2a73-A |
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PDB Code
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2a73 |
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Chain
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A |
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click to enlarge
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Title
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Human Complement Component C3 |
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Classification
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IMMUNE SYSTEM |
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Compound
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Complement C3 |
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Source
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ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; |
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Sequence
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A: |
SPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDF
PGKKLVLSSEKTVLTPATNHMGNVTFTIPANRERNKFVTV
QATFGTQVVEKVVLVSLQSGYLFIQTDKTIYTPGSTVLYR
IFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGV
LPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYV
LPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGT
AFVIFGIQDGEQRISLPESLKRIPIEDGSGEVVLSRKVLL
DGVLRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVT
SPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVA
VQGEDTVQSLTQGDGVAKLSINTHPSQKPLSITVRTKKQE
LSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGET
LNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREP
GQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADS
VWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHG
ARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPG
SGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQP
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Description
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Functional site
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1)
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chain |
A |
| residue |
48 |
| type |
SITE |
| sequence |
S
|
| description |
Cleavage; by C3 convertase
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| source |
Swiss-Prot : SWS_FT_FI2
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2)
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chain |
A |
| residue |
275 |
| type |
SITE |
| sequence |
S
|
| description |
Cleavage; by C3 convertase
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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3)
|
chain |
A |
| residue |
281 |
| type |
SITE |
| sequence |
S
|
| description |
Cleavage; by C3 convertase
|
| source |
Swiss-Prot : SWS_FT_FI2
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