eF-site ID 2a69-KLMNOP PDB Code 2a69 Chain K, L, M, N, O, P click to enlarge Title Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin Classification TRANSFERASE Compound DNA-directed RNA polymerase alpha chain Source ORGANISM_SCIENTIFIC: Thermus thermophilus; Sequence K:  MLDSKLKAPVFTVRTQGREYGEFVLEPLERGFGVTLGNPL RRILLSSIPGTAVTSVYIEDVLHEFSTIPGVKEDVVEIIL NLKELVVRFLNPSLQTVTLLLKAEGPKEVKARDFLPVADV EIMNPDLHIATLEEGGRLNMEVRVDRGVGYVPAEKHGIKD RINAIPVDAVFSPVRRVAFQVEDTRLGQRTDLDKLTLRIW TDGSVTPLEALNQAVEILREHLTYFSNPQ L:  MLDSKLKAPVFTVRTQGREYGEFVLEPLERGFGVTLGNPL RRILLSSIPGTAVTSVYIEDVLHEFSTIPGVKEDVVEIIL NLKELVVRFLNPSLQTVTLLLKAEGPKEVKARDFLPVADV EIMNPDLHIATLEEGGRLNMEVRVDRGVGYVPAEKHGIKD RINAIPVDAVFSPVRRVAFQVEDTRLGQRTDLDKLTLRIW TDGSVTPLEALNQAVEILREHLTYFSNPQ M:  MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRE NVGIQAAFRETFPIEEEDKGKGGLVLDFLEYRLGEPPFPQ DECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPL MTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIA SIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVL GYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFT LLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEK LGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGH EVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERML MGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNP LSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICP VETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVT DEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGE PVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALM GSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEED GEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQR PRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFD GYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPE RITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTS FKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIV VRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLA NRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRM NLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQ AFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPE EQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHM VEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWAL EAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPS VPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASKR N:  KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPER DGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVT KSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSAT ELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYREL RYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDG VALYRFPRRVRVEYVKKERAGLRLPLAAWVEKEAYKPGEI LAELPEPYLFGDKIVAAIDPEEEVIAEAEGVVHLHEPASI LVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYG RVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEAL EKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMI LEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNR LKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTN PGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVV GPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAA RRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGI QAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSS FAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYIT QVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRE TSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRL ETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKD LVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDD AVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQIL QLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQ QIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFIS SHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCG TTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREV EVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLT CQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPG TQLTMRTFHTGGVAGAADITQGLPRVIELFEARRPKAKAV ISEIDGVVRIEETEEKLSVFVESEGFSKEYKLPKEARLLV KDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVEEIQ KVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQ VLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKS WLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIP AGTGSDFVRFTQVVDQKTLKAIEEARKEAVEA O:  AEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHGFKNTVLE PEERPKMQTLEGLFDDPNAETWAMKELLTGRLVFGENLVP EDRLQKEMERIYPGE P:  KISTSDPVRQYLHEIGQVPLLTLEEEVELARKVEEGMEAI KKLSEITGLDPDLIREVVRAKILGSARVRHIPGLKETLDP KTVEEIDQKLKSLPKEHKRYLHIAREGEAARQHLIEANLR LVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRF KFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSR TARQLQQELGREPTYEEIAEAMGPGWDAKRVEETLKIAQE PVSLETPIGDEKDSFYGDFIPDEHLPSPVDAATQSLLSEE LEKALSKLSEREAMVLKLRKGLIDGEEVGAFFGVTRERIR QIENKALRKLKYHESRTRKLRDFLD Description Functional site 1) chain P residue 241 type sequence W description BINDING SITE FOR RESIDUE MG C 9065 source : HC1 2) chain P residue 149 type sequence E description BINDING SITE FOR RESIDUE MG D 9039 source : NC1 3) chain K residue 58 type sequence I description BINDING SITE FOR RESIDUE MG K 9180 source : XC9 4) chain K residue 59 type sequence E description BINDING SITE FOR RESIDUE MG K 9180 source : XC9 5) chain K residue 60 type sequence D description BINDING SITE FOR RESIDUE MG K 9180 source : XC9 6) chain K residue 139 type sequence N description BINDING SITE FOR RESIDUE MG K 9180 source : XC9 7) chain K residue 51 type sequence T description BINDING SITE FOR RESIDUE MG K 9188 source : YC1 8) chain K residue 170 type sequence V description BINDING SITE FOR RESIDUE MG K 9188 source : YC1 9) chain K residue 13 type sequence V description BINDING SITE FOR RESIDUE MG K 9191 source : YC2 10) chain L residue 229 type sequence Q description BINDING SITE FOR RESIDUE MG K 9191 source : YC2 11) chain K residue 57 type sequence Y description BINDING SITE FOR RESIDUE MG K 9213 source : YC3 12) chain K residue 141 type sequence E description BINDING SITE FOR RESIDUE MG K 9213 source : YC3 13) chain K residue 160 type sequence D description BINDING SITE FOR RESIDUE MG K 9213 source : YC3 14) chain K residue 161 type sequence R description BINDING SITE FOR RESIDUE MG K 9213 source : YC3 15) chain K residue 7 type sequence K description BINDING SITE FOR RESIDUE MG K 9223 source : YC4 16) chain K residue 27 type sequence P description BINDING SITE FOR RESIDUE MG K 9223 source : YC4 17) chain K residue 28 type sequence L description BINDING SITE FOR RESIDUE MG K 9223 source : YC4 18) chain K residue 118 type sequence A description BINDING SITE FOR RESIDUE MG K 9244 source : YC5 19) chain K residue 119 type sequence D description BINDING SITE FOR RESIDUE MG K 9244 source : YC5 20) chain K residue 137 type sequence R description BINDING SITE FOR RESIDUE MG K 9251 source : YC6 21) chain K residue 139 type sequence N description BINDING SITE FOR RESIDUE MG K 9251 source : YC6 22) chain K residue 95 type sequence Q description BINDING SITE FOR RESIDUE MG K 9257 source : YC7 23) chain K residue 60 type sequence D description BINDING SITE FOR RESIDUE MG K 9264 source : YC8 24) chain K residue 137 type sequence R description BINDING SITE FOR RESIDUE MG K 9264 source : YC8 25) chain K residue 16 type sequence Q description BINDING SITE FOR RESIDUE MG K 9290 source : YC9 26) chain K residue 52 type sequence A description BINDING SITE FOR RESIDUE MG K 9410 source : ZC2 27) chain K residue 54 type sequence T description BINDING SITE FOR RESIDUE MG K 9410 source : ZC2 28) chain K residue 171 type sequence F description BINDING SITE FOR RESIDUE MG K 9410 source : ZC2 29) chain L residue 28 type sequence L description BINDING SITE FOR RESIDUE MG L 9182 source : ZC5 30) chain L residue 29 type sequence E description BINDING SITE FOR RESIDUE MG L 9182 source : ZC5 31) chain L residue 189 type sequence R description BINDING SITE FOR RESIDUE MG L 9182 source : ZC5 32) chain L residue 191 type sequence D description BINDING SITE FOR RESIDUE MG L 9182 source : ZC5 33) chain L residue 192 type sequence L description BINDING SITE FOR RESIDUE MG L 9182 source : ZC5 34) chain L residue 51 type sequence T description BINDING SITE FOR RESIDUE MG L 9183 source : ZC6 35) chain L residue 170 type sequence V description BINDING SITE FOR RESIDUE MG L 9183 source : ZC6 36) chain L residue 172 type sequence S description BINDING SITE FOR RESIDUE MG L 9183 source : ZC6 37) chain L residue 202 type sequence D description BINDING SITE FOR RESIDUE MG L 9183 source : ZC6 38) chain L residue 93 type sequence S description BINDING SITE FOR RESIDUE MG L 9218 source : ZC7 39) chain L residue 159 type sequence K description BINDING SITE FOR RESIDUE MG L 9245 source : ZC8 40) chain L residue 219 type sequence R description BINDING SITE FOR RESIDUE MG L 9246 source : ZC9 41) chain L residue 69 type sequence P description BINDING SITE FOR RESIDUE MG L 9252 source : AD1 42) chain L residue 135 type sequence G description BINDING SITE FOR RESIDUE MG L 9252 source : AD1 43) chain L residue 60 type sequence D description BINDING SITE FOR RESIDUE MG L 9278 source : AD2 44) chain L residue 13 type sequence V description BINDING SITE FOR RESIDUE MG L 9289 source : AD3 45) chain L residue 14 type sequence R description BINDING SITE FOR RESIDUE MG L 9289 source : AD3 46) chain L residue 133 type sequence E description BINDING SITE FOR RESIDUE MG L 9306 source : AD4 47) chain L residue 59 type sequence E description BINDING SITE FOR RESIDUE MG L 9307 source : AD5 48) chain L residue 62 type sequence L description BINDING SITE FOR RESIDUE MG L 9309 source : AD6 49) chain L residue 118 type sequence A description BINDING SITE FOR RESIDUE MG L 9314 source : AD7 50) chain L residue 119 type sequence D description BINDING SITE FOR RESIDUE MG L 9314 source : AD7 51) chain L residue 93 type sequence S description BINDING SITE FOR RESIDUE MG L 9437 source : AD8 52) chain M residue 134 type sequence R description BINDING SITE FOR RESIDUE RPT M 8002 source : AD9 53) chain M residue 389 type sequence S description BINDING SITE FOR RESIDUE RPT M 8002 source : AD9 54) chain M residue 390 type sequence Q description BINDING SITE FOR RESIDUE RPT M 8002 source : AD9 55) chain M residue 392 type sequence S description BINDING SITE FOR RESIDUE RPT M 8002 source : AD9 56) chain M residue 393 type sequence Q description BINDING SITE FOR RESIDUE RPT M 8002 source : AD9 57) chain M residue 394 type sequence F description BINDING SITE FOR RESIDUE RPT M 8002 source : AD9 58) chain M residue 395 type sequence K description BINDING SITE FOR RESIDUE RPT M 8002 source : AD9 59) chain M residue 396 type sequence D description BINDING SITE FOR RESIDUE RPT M 8002 source : AD9 60) chain M residue 406 type sequence H description BINDING SITE FOR RESIDUE RPT M 8002 source : AD9 61) chain M residue 409 type sequence R description BINDING SITE FOR RESIDUE RPT M 8002 source : AD9 62) chain M residue 411 type sequence S description BINDING SITE FOR RESIDUE RPT M 8002 source : AD9 63) chain M residue 413 type sequence L description BINDING SITE FOR RESIDUE RPT M 8002 source : AD9 64) chain M residue 444 type sequence P description BINDING SITE FOR RESIDUE RPT M 8002 source : AD9 65) chain M residue 452 type sequence I description BINDING SITE FOR RESIDUE RPT M 8002 source : AD9 66) chain M residue 1000 type sequence M description BINDING SITE FOR RESIDUE RPT M 8002 source : AD9 67) chain M residue 1002 type sequence E description BINDING SITE FOR RESIDUE RPT M 8002 source : AD9 68) chain M residue 448 type sequence N description BINDING SITE FOR RESIDUE MG M 9190 source : BD1 69) chain M residue 1116 type sequence A description BINDING SITE FOR RESIDUE MG M 9195 source : BD2 70) chain M residue 769 type sequence P description BINDING SITE FOR RESIDUE MG M 9196 source : BD3 71) chain M residue 770 type sequence E description BINDING SITE FOR RESIDUE MG M 9196 source : BD3 72) chain N residue 65 type sequence R description BINDING SITE FOR RESIDUE MG M 9196 source : BD3 73) chain P residue 374 type sequence G description BINDING SITE FOR RESIDUE MG M 9196 source : BD3 74) chain M residue 951 type sequence G description BINDING SITE FOR RESIDUE MG M 9201 source : BD4 75) chain M residue 952 type sequence L description BINDING SITE FOR RESIDUE MG M 9201 source : BD4 76) chain M residue 969 type sequence Q description BINDING SITE FOR RESIDUE MG M 9201 source : BD4 77) chain M residue 219 type sequence Q description BINDING SITE FOR RESIDUE MG M 9203 source : BD5 78) chain M residue 220 type sequence G description BINDING SITE FOR RESIDUE MG M 9203 source : BD5 79) chain M residue 1010 type sequence T description BINDING SITE FOR RESIDUE MG M 9205 source : BD6 80) chain M residue 1026 type sequence Q description BINDING SITE FOR RESIDUE MG M 9205 source : BD6 81) chain N residue 651 type sequence E description BINDING SITE FOR RESIDUE MG M 9205 source : BD6 82) chain M residue 775 type sequence R description BINDING SITE FOR RESIDUE MG M 9208 source : BD7 83) chain P residue 421 type sequence F description BINDING SITE FOR RESIDUE MG M 9208 source : BD7 84) chain M residue 714 type sequence D description BINDING SITE FOR RESIDUE MG M 9210 source : BD8 85) chain M residue 820 type sequence R description BINDING SITE FOR RESIDUE MG M 9210 source : BD8 86) chain M residue 332 type sequence R description BINDING SITE FOR RESIDUE MG M 9212 source : BD9 87) chain M residue 464 type sequence L description BINDING SITE FOR RESIDUE MG M 9212 source : BD9 88) chain M residue 465 type sequence G description BINDING SITE FOR RESIDUE MG M 9212 source : BD9 89) chain M residue 466 type sequence F description BINDING SITE FOR RESIDUE MG M 9212 source : BD9 90) chain M residue 204 type sequence Q description BINDING SITE FOR RESIDUE MG M 9219 source : CD1 91) chain M residue 222 type sequence M description BINDING SITE FOR RESIDUE MG M 9219 source : CD1 92) chain M residue 224 type sequence E description BINDING SITE FOR RESIDUE MG M 9219 source : CD1 93) chain M residue 225 type sequence S description BINDING SITE FOR RESIDUE MG M 9219 source : CD1 94) chain M residue 228 type sequence A description BINDING SITE FOR RESIDUE MG M 9219 source : CD1 95) chain M residue 318 type sequence P description BINDING SITE FOR RESIDUE MG M 9220 source : CD2 96) chain M residue 1105 type sequence K description BINDING SITE FOR RESIDUE MG M 9225 source : CD5 97) chain M residue 1104 type sequence E description BINDING SITE FOR RESIDUE MG M 9227 source : CD6 98) chain M residue 1061 type sequence E description BINDING SITE FOR RESIDUE MG M 9230 source : CD7 99) chain M residue 706 type sequence E description BINDING SITE FOR RESIDUE MG M 9234 source : CD8 100) chain M residue 626 type sequence R description BINDING SITE FOR RESIDUE MG M 9239 source : DD1 101) chain M residue 637 type sequence L description BINDING SITE FOR RESIDUE MG M 9239 source : DD1 102) chain M residue 638 type sequence D description BINDING SITE FOR RESIDUE MG M 9239 source : DD1 103) chain M residue 639 type sequence Q description BINDING SITE FOR RESIDUE MG M 9239 source : DD1 104) chain M residue 1061 type sequence E description BINDING SITE FOR RESIDUE MG M 9241 source : DD2 105) chain M residue 1080 type sequence S description BINDING SITE FOR RESIDUE MG M 9241 source : DD2 106) chain M residue 368 type sequence T description BINDING SITE FOR RESIDUE MG M 9242 source : DD3 107) chain M residue 150 type sequence P description BINDING SITE FOR RESIDUE MG M 9247 source : DD4 108) chain M residue 151 type sequence D description BINDING SITE FOR RESIDUE MG M 9247 source : DD4 109) chain M residue 158 type sequence Y description BINDING SITE FOR RESIDUE MG M 9247 source : DD4 110) chain M residue 55 type sequence E description BINDING SITE FOR RESIDUE MG M 9248 source : DD5 111) chain M residue 57 type sequence E description BINDING SITE FOR RESIDUE MG M 9248 source : DD5 112) chain M residue 998 type sequence Y description BINDING SITE FOR RESIDUE MG M 9250 source : DD6 113) chain M residue 1000 type sequence M description BINDING SITE FOR RESIDUE MG M 9250 source : DD6 114) chain M residue 512 type sequence R description BINDING SITE FOR RESIDUE MG M 9256 source : DD7 115) chain M residue 461 type sequence V description BINDING SITE FOR RESIDUE MG M 9260 source : DD8 116) chain M residue 736 type sequence D description BINDING SITE FOR RESIDUE MG M 9261 source : DD9 117) chain M residue 1024 type sequence K description BINDING SITE FOR RESIDUE MG M 9263 source : ED1 118) chain M residue 1041 type sequence E description BINDING SITE FOR RESIDUE MG M 9268 source : ED2 119) chain N residue 1463 type sequence K description BINDING SITE FOR RESIDUE MG M 9268 source : ED2 120) chain M residue 247 type sequence P description BINDING SITE FOR RESIDUE MG M 9275 source : ED4 121) chain M residue 651 type sequence K description BINDING SITE FOR RESIDUE MG M 9295 source : ED5 122) chain M residue 652 type sequence G description BINDING SITE FOR RESIDUE MG M 9295 source : ED5 123) chain M residue 653 type sequence D description BINDING SITE FOR RESIDUE MG M 9295 source : ED5 124) chain M residue 836 type sequence G description BINDING SITE FOR RESIDUE MG M 9299 source : ED6 125) chain M residue 999 type sequence H description BINDING SITE FOR RESIDUE MG M 9299 source : ED6 126) chain N residue 630 type sequence V description BINDING SITE FOR RESIDUE MG M 9299 source : ED6 127) chain M residue 492 type sequence D description BINDING SITE FOR RESIDUE MG M 9300 source : ED7 128) chain M residue 642 type sequence R description BINDING SITE FOR RESIDUE MG M 9310 source : ED8 129) chain M residue 644 type sequence V description BINDING SITE FOR RESIDUE MG M 9310 source : ED8 130) chain M residue 647 type sequence Q description BINDING SITE FOR RESIDUE MG M 9310 source : ED8 131) chain M residue 707 type sequence R description BINDING SITE FOR RESIDUE MG M 9312 source : ED9 132) chain M residue 695 type sequence L description BINDING SITE FOR RESIDUE MG M 9319 source : FD1 133) chain M residue 1106 type sequence D description BINDING SITE FOR RESIDUE MG M 9320 source : FD2 134) chain M residue 811 type sequence P description BINDING SITE FOR RESIDUE MG M 9321 source : FD3 135) chain M residue 976 type sequence D description BINDING SITE FOR RESIDUE MG M 9324 source : FD4 136) chain M residue 978 type sequence R description BINDING SITE FOR RESIDUE MG M 9324 source : FD4 137) chain M residue 979 type sequence T description BINDING SITE FOR RESIDUE MG M 9324 source : FD4 138) chain M residue 608 type sequence G description BINDING SITE FOR RESIDUE MG M 9400 source : FD5 139) chain M residue 639 type sequence Q description BINDING SITE FOR RESIDUE MG M 9400 source : FD5 140) chain M residue 706 type sequence E description BINDING SITE FOR RESIDUE MG M 9401 source : FD6 141) chain M residue 708 type sequence Y description BINDING SITE FOR RESIDUE MG M 9401 source : FD6 142) chain M residue 1004 type sequence K description BINDING SITE FOR RESIDUE MG M 9401 source : FD6 143) chain M residue 838 type sequence K description BINDING SITE FOR RESIDUE MG M 9407 source : FD7 144) chain M residue 57 type sequence E description BINDING SITE FOR RESIDUE MG M 9409 source : FD8 145) chain M residue 198 type sequence R description BINDING SITE FOR RESIDUE MG M 9411 source : FD9 146) chain M residue 228 type sequence A description BINDING SITE FOR RESIDUE MG M 9411 source : FD9 147) chain M residue 229 type sequence M description BINDING SITE FOR RESIDUE MG M 9411 source : FD9 148) chain M residue 230 type sequence R description BINDING SITE FOR RESIDUE MG M 9411 source : FD9 149) chain M residue 20 type sequence E description BINDING SITE FOR RESIDUE MG M 9416 source : GD2 150) chain M residue 205 type sequence E description BINDING SITE FOR RESIDUE MG M 9424 source : GD3 151) chain M residue 1104 type sequence E description BINDING SITE FOR RESIDUE MG M 9440 source : GD5 152) chain M residue 1105 type sequence K description BINDING SITE FOR RESIDUE MG M 9440 source : GD5 153) chain M residue 224 type sequence E description BINDING SITE FOR RESIDUE MG M 9442 source : GD7 154) chain M residue 365 type sequence D description BINDING SITE FOR RESIDUE MG M 9447 source : GD8 155) chain M residue 366 type sequence S description BINDING SITE FOR RESIDUE MG M 9447 source : GD8 156) chain M residue 1 type sequence M description BINDING SITE FOR RESIDUE MG M 9452 source : GD9 157) chain M residue 180 type sequence G description BINDING SITE FOR RESIDUE MG M 9471 source : HD1 158) chain M residue 49 type sequence R description BINDING SITE FOR RESIDUE MG M 9486 source : HD3 159) chain N residue 58 type sequence C description BINDING SITE FOR RESIDUE ZN N 7059 source : HD4 160) chain N residue 60 type sequence C description BINDING SITE FOR RESIDUE ZN N 7059 source : HD4 161) chain N residue 73 type sequence C description BINDING SITE FOR RESIDUE ZN N 7059 source : HD4 162) chain N residue 76 type sequence C description BINDING SITE FOR RESIDUE ZN N 7059 source : HD4 163) chain N residue 1112 type sequence C description BINDING SITE FOR RESIDUE ZN N 7113 source : HD5 164) chain N residue 1194 type sequence C description BINDING SITE FOR RESIDUE ZN N 7113 source : HD5 165) chain N residue 1201 type sequence C description BINDING SITE FOR RESIDUE ZN N 7113 source : HD5 166) chain N residue 1204 type sequence C description BINDING SITE FOR RESIDUE ZN N 7113 source : HD5 167) chain N residue 920 type sequence L description BINDING SITE FOR RESIDUE MG N 9179 source : HD6 168) chain N residue 1212 type sequence A description BINDING SITE FOR RESIDUE MG N 9179 source : HD6 169) chain N residue 1213 type sequence R description BINDING SITE FOR RESIDUE MG N 9179 source : HD6 170) chain N residue 1196 type sequence T description BINDING SITE FOR RESIDUE MG N 9181 source : HD7 171) chain N residue 1197 type sequence R description BINDING SITE FOR RESIDUE MG N 9181 source : HD7 172) chain N residue 786 type sequence I description BINDING SITE FOR RESIDUE MG N 9184 source : HD8 173) chain N residue 906 type sequence Q description BINDING SITE FOR RESIDUE MG N 9184 source : HD8 174) chain N residue 907 type sequence E description BINDING SITE FOR RESIDUE MG N 9184 source : HD8 175) chain N residue 908 type sequence K description BINDING SITE FOR RESIDUE MG N 9184 source : HD8 176) chain N residue 1026 type sequence S description BINDING SITE FOR RESIDUE MG N 9184 source : HD8 177) chain N residue 1027 type sequence G description BINDING SITE FOR RESIDUE MG N 9184 source : HD8 178) chain N residue 1130 type sequence R description BINDING SITE FOR RESIDUE MG N 9186 source : ID1 179) chain N residue 1131 type sequence S description BINDING SITE FOR RESIDUE MG N 9186 source : ID1 180) chain N residue 1132 type sequence L description BINDING SITE FOR RESIDUE MG N 9186 source : ID1 181) chain N residue 143 type sequence N description BINDING SITE FOR RESIDUE MG N 9192 source : ID3 182) chain N residue 144 type sequence G description BINDING SITE FOR RESIDUE MG N 9192 source : ID3 183) chain N residue 145 type sequence V description BINDING SITE FOR RESIDUE MG N 9192 source : ID3 184) chain N residue 961 type sequence K description BINDING SITE FOR RESIDUE MG N 9193 source : ID4 185) chain N residue 251 type sequence F description BINDING SITE FOR RESIDUE MG N 9194 source : ID5 186) chain N residue 1390 type sequence L description BINDING SITE FOR RESIDUE MG N 9199 source : ID6 187) chain N residue 1391 type sequence E description BINDING SITE FOR RESIDUE MG N 9199 source : ID6 188) chain N residue 107 type sequence D description BINDING SITE FOR RESIDUE MG N 9200 source : ID7 189) chain N residue 109 type sequence P description BINDING SITE FOR RESIDUE MG N 9200 source : ID7 190) chain N residue 111 type sequence K description BINDING SITE FOR RESIDUE MG N 9200 source : ID7 191) chain N residue 1359 type sequence Q description BINDING SITE FOR RESIDUE MG N 9206 source : ID8 192) chain N residue 1439 type sequence S description BINDING SITE FOR RESIDUE MG N 9207 source : ID9 193) chain N residue 1443 type sequence T description BINDING SITE FOR RESIDUE MG N 9207 source : ID9 194) chain N residue 706 type sequence P description BINDING SITE FOR RESIDUE MG N 9211 source : JD1 195) chain N residue 736 type sequence F description BINDING SITE FOR RESIDUE MG N 9211 source : JD1 196) chain N residue 737 type sequence N description BINDING SITE FOR RESIDUE MG N 9211 source : JD1 197) chain N residue 1197 type sequence R description BINDING SITE FOR RESIDUE MG N 9214 source : JD2 198) chain N residue 1373 type sequence R description BINDING SITE FOR RESIDUE MG N 9214 source : JD2 199) chain N residue 1374 type sequence Q description BINDING SITE FOR RESIDUE MG N 9214 source : JD2 200) chain N residue 1377 type sequence K description BINDING SITE FOR RESIDUE MG N 9214 source : JD2 201) chain N residue 188 type sequence G description BINDING SITE FOR RESIDUE MG N 9215 source : JD3 202) chain N residue 441 type sequence R description BINDING SITE FOR RESIDUE MG N 9215 source : JD3 203) chain N residue 1116 type sequence N description BINDING SITE FOR RESIDUE MG N 9217 source : JD4 204) chain N residue 1096 type sequence R description BINDING SITE FOR RESIDUE MG N 9221 source : JD5 205) chain N residue 183 type sequence E description BINDING SITE FOR RESIDUE MG N 9229 source : JD6 206) chain N residue 187 type sequence K description BINDING SITE FOR RESIDUE MG N 9229 source : JD6 207) chain N residue 965 type sequence E description BINDING SITE FOR RESIDUE MG N 9231 source : JD7 208) chain N residue 1196 type sequence T description BINDING SITE FOR RESIDUE MG N 9232 source : JD8 209) chain N residue 1235 type sequence Q description BINDING SITE FOR RESIDUE MG N 9233 source : JD9 210) chain N residue 1237 type sequence T description BINDING SITE FOR RESIDUE MG N 9233 source : JD9 211) chain N residue 530 type sequence V description BINDING SITE FOR RESIDUE MG N 9236 source : KD1 212) chain N residue 531 type sequence D description BINDING SITE FOR RESIDUE MG N 9236 source : KD1 213) chain N residue 532 type sequence G description BINDING SITE FOR RESIDUE MG N 9236 source : KD1 214) chain N residue 772 type sequence P description BINDING SITE FOR RESIDUE MG N 9238 source : KD2 215) chain N residue 1208 type sequence D description BINDING SITE FOR RESIDUE MG N 9238 source : KD2 216) chain N residue 1367 type sequence H description BINDING SITE FOR RESIDUE MG N 9238 source : KD2 217) chain N residue 1468 type sequence L description BINDING SITE FOR RESIDUE MG N 9240 source : KD3 218) chain N residue 133 type sequence I description BINDING SITE FOR RESIDUE MG N 9243 source : KD4 219) chain N residue 135 type sequence L description BINDING SITE FOR RESIDUE MG N 9243 source : KD4 220) chain N residue 151 type sequence Q description BINDING SITE FOR RESIDUE MG N 9243 source : KD4 221) chain N residue 153 type sequence L description BINDING SITE FOR RESIDUE MG N 9243 source : KD4 222) chain N residue 1431 type sequence T description BINDING SITE FOR RESIDUE MG N 9249 source : KD5 223) chain N residue 1432 type sequence K description BINDING SITE FOR RESIDUE MG N 9249 source : KD5 224) chain N residue 187 type sequence K description BINDING SITE FOR RESIDUE MG N 9259 source : KD6 225) chain N residue 441 type sequence R description BINDING SITE FOR RESIDUE MG N 9259 source : KD6 226) chain N residue 1165 type sequence Y description BINDING SITE FOR RESIDUE MG N 9267 source : KD8 227) chain N residue 1501 type sequence E description BINDING SITE FOR RESIDUE MG N 9269 source : KD9 228) chain N residue 1502 type sequence A description BINDING SITE FOR RESIDUE MG N 9269 source : KD9 229) chain N residue 1416 type sequence A description BINDING SITE FOR RESIDUE MG N 9270 source : LD1 230) chain N residue 1417 type sequence W description BINDING SITE FOR RESIDUE MG N 9270 source : LD1 231) chain N residue 576 type sequence E description BINDING SITE FOR RESIDUE MG N 9271 source : LD2 232) chain N residue 579 type sequence D description BINDING SITE FOR RESIDUE MG N 9271 source : LD2 233) chain N residue 580 type sequence A description BINDING SITE FOR RESIDUE MG N 9271 source : LD2 234) chain N residue 583 type sequence D description BINDING SITE FOR RESIDUE MG N 9271 source : LD2 235) chain N residue 587 type sequence R description BINDING SITE FOR RESIDUE MG N 9271 source : LD2 236) chain N residue 1266 type sequence R description BINDING SITE FOR RESIDUE MG N 9274 source : LD3 237) chain N residue 494 type sequence K description BINDING SITE FOR RESIDUE MG N 9276 source : LD4 238) chain N residue 1318 type sequence Y description BINDING SITE FOR RESIDUE MG N 9286 source : LD5 239) chain N residue 811 type sequence E description BINDING SITE FOR RESIDUE MG N 9287 source : LD6 240) chain N residue 157 type sequence E description BINDING SITE FOR RESIDUE MG N 9288 source : LD7 241) chain N residue 1033 type sequence Q description BINDING SITE FOR RESIDUE MG N 9292 source : LD8 242) chain N residue 139 type sequence G description BINDING SITE FOR RESIDUE MG N 9298 source : MD1 243) chain N residue 140 type sequence A description BINDING SITE FOR RESIDUE MG N 9298 source : MD1 244) chain N residue 141 type sequence I description BINDING SITE FOR RESIDUE MG N 9298 source : MD1 245) chain N residue 146 type sequence P description BINDING SITE FOR RESIDUE MG N 9298 source : MD1 246) chain N residue 147 type sequence V description BINDING SITE FOR RESIDUE MG N 9298 source : MD1 247) chain N residue 529 type sequence Q description BINDING SITE FOR RESIDUE MG N 9302 source : MD2 248) chain N residue 1327 type sequence R description BINDING SITE FOR RESIDUE MG N 9303 source : MD3 249) chain N residue 488 type sequence R description BINDING SITE FOR RESIDUE MG N 9304 source : MD4 250) chain N residue 1242 type sequence H description BINDING SITE FOR RESIDUE MG N 9313 source : MD6 251) chain N residue 213 type sequence V description BINDING SITE FOR RESIDUE MG N 9316 source : MD7 252) chain N residue 390 type sequence P description BINDING SITE FOR RESIDUE MG N 9316 source : MD7 253) chain N residue 1116 type sequence N description BINDING SITE FOR RESIDUE MG N 9317 source : MD8 254) chain N residue 403 type sequence F description BINDING SITE FOR RESIDUE MG N 9318 source : MD9 255) chain N residue 1419 type sequence P description BINDING SITE FOR RESIDUE MG N 9322 source : ND1 256) chain N residue 921 type sequence R description BINDING SITE FOR RESIDUE MG N 9323 source : ND2 257) chain N residue 466 type sequence K description BINDING SITE FOR RESIDUE MG N 9326 source : ND3 258) chain N residue 187 type sequence K description BINDING SITE FOR RESIDUE MG N 9327 source : ND4 259) chain N residue 113 type sequence G description BINDING SITE FOR RESIDUE MG N 9398 source : ND5 260) chain N residue 116 type sequence L description BINDING SITE FOR RESIDUE MG N 9398 source : ND5 261) chain N residue 118 type sequence L description BINDING SITE FOR RESIDUE MG N 9398 source : ND5 262) chain N residue 119 type sequence S description BINDING SITE FOR RESIDUE MG N 9398 source : ND5 263) chain N residue 120 type sequence A description BINDING SITE FOR RESIDUE MG N 9398 source : ND5 264) chain N residue 484 type sequence P description BINDING SITE FOR RESIDUE MG N 9402 source : ND6 265) chain N residue 485 type sequence S description BINDING SITE FOR RESIDUE MG N 9402 source : ND6 266) chain N residue 488 type sequence R description BINDING SITE FOR RESIDUE MG N 9402 source : ND6 267) chain N residue 6 type sequence R description BINDING SITE FOR RESIDUE MG N 9415 source : ND7 268) chain N residue 1482 type sequence R description BINDING SITE FOR RESIDUE MG N 9415 source : ND7 269) chain N residue 1048 type sequence P description BINDING SITE FOR RESIDUE MG N 9417 source : ND8 270) chain N residue 901 type sequence Q description BINDING SITE FOR RESIDUE MG N 9418 source : ND9 271) chain N residue 684 type sequence K description BINDING SITE FOR RESIDUE MG N 9419 source : OD1 272) chain N residue 686 type sequence E description BINDING SITE FOR RESIDUE MG N 9419 source : OD1 273) chain N residue 903 type sequence D description BINDING SITE FOR RESIDUE MG N 9426 source : OD4 274) chain N residue 238 type sequence P description BINDING SITE FOR RESIDUE MG N 9429 source : OD7 275) chain N residue 240 type sequence E description BINDING SITE FOR RESIDUE MG N 9429 source : OD7 276) chain N residue 1252 type sequence I description BINDING SITE FOR RESIDUE MG N 9430 source : OD8 277) chain N residue 196 type sequence V description BINDING SITE FOR RESIDUE MG N 9448 source : OD9 278) chain N residue 204 type sequence L description BINDING SITE FOR RESIDUE MG N 9449 source : PD1 279) chain N residue 1058 type sequence R description BINDING SITE FOR RESIDUE MG N 9450 source : PD2 280) chain L residue 77 type sequence E description BINDING SITE FOR RESIDUE MG N 9465 source : PD3 281) chain N residue 872 type sequence R description BINDING SITE FOR RESIDUE MG N 9465 source : PD3 282) chain M residue 1097 type sequence L description BINDING SITE FOR RESIDUE MG N 9467 source : PD4 283) chain N residue 11 type sequence A description BINDING SITE FOR RESIDUE MG N 9467 source : PD4 284) chain N residue 12 type sequence L description BINDING SITE FOR RESIDUE MG N 9467 source : PD4 285) chain N residue 104 type sequence F description BINDING SITE FOR RESIDUE MG N 9467 source : PD4 286) chain N residue 1451 type sequence A description BINDING SITE FOR RESIDUE MG N 9467 source : PD4 287) chain N residue 527 type sequence M description BINDING SITE FOR RESIDUE MG N 9473 source : PD6 288) chain N residue 529 type sequence Q description BINDING SITE FOR RESIDUE MG N 9484 source : PD7 289) chain O residue 34 type sequence G description BINDING SITE FOR RESIDUE MG O 9197 source : PD8 290) chain O residue 35 type sequence F description BINDING SITE FOR RESIDUE MG O 9197 source : PD8 291) chain O residue 94 type sequence P description BINDING SITE FOR RESIDUE MG O 9197 source : PD8 292) chain O residue 95 type sequence G description BINDING SITE FOR RESIDUE MG O 9197 source : PD8 293) chain O residue 50 type sequence T description BINDING SITE FOR RESIDUE MG O 9198 source : PD9 294) chain O residue 50 type sequence T description BINDING SITE FOR RESIDUE MG O 9254 source : QD1 295) chain N residue 640 type sequence H description BINDING SITE FOR RESIDUE MG O 9266 source : QD2 296) chain O residue 2 type sequence A description BINDING SITE FOR RESIDUE MG O 9266 source : QD2 297) chain O residue 3 type sequence E description BINDING SITE FOR RESIDUE MG O 9266 source : QD2 298) chain O residue 8 type sequence K description BINDING SITE FOR RESIDUE MG O 9420 source : QD3 299) chain P residue 340 type sequence S description BINDING SITE FOR RESIDUE MG P 9189 source : QD5 300) chain P residue 82 type sequence R description BINDING SITE FOR RESIDUE MG P 9202 source : QD6 301) chain P residue 165 type sequence S description BINDING SITE FOR RESIDUE MG P 9209 source : QD7 302) chain M residue 1072 type sequence K description BINDING SITE FOR RESIDUE MG P 9226 source : QD9 303) chain P residue 349 type sequence L description BINDING SITE FOR RESIDUE MG P 9226 source : QD9 304) chain N residue 669 type sequence N description BINDING SITE FOR RESIDUE MG P 9228 source : RD1 305) chain P residue 417 type sequence K description BINDING SITE FOR RESIDUE MG P 9228 source : RD1 306) chain P residue 418 type sequence L description BINDING SITE FOR RESIDUE MG P 9228 source : RD1 307) chain P residue 419 type sequence R description BINDING SITE FOR RESIDUE MG P 9228 source : RD1 308) chain P residue 420 type sequence D description BINDING SITE FOR RESIDUE MG P 9228 source : RD1 309) chain P residue 205 type sequence R description BINDING SITE FOR RESIDUE MG P 9255 source : RD3 310) chain P residue 228 type sequence E description BINDING SITE FOR RESIDUE MG P 9277 source : RD4 311) chain P residue 273 type sequence R description BINDING SITE FOR RESIDUE MG P 9280 source : RD5 312) chain P residue 277 type sequence Q description BINDING SITE FOR RESIDUE MG P 9285 source : RD6 313) chain P residue 280 type sequence Q description BINDING SITE FOR RESIDUE MG P 9285 source : RD6 314) chain P residue 403 type sequence K description BINDING SITE FOR RESIDUE MG P 9297 source : RD7 315) chain P residue 407 type sequence K description BINDING SITE FOR RESIDUE MG P 9297 source : RD7 316) chain P residue 82 type sequence R description BINDING SITE FOR RESIDUE MG P 9325 source : RD9 317) chain P residue 364 type sequence R description BINDING SITE FOR RESIDUE MG P 9399 source : SD1 318) chain P residue 390 type sequence F description BINDING SITE FOR RESIDUE MG P 9399 source : SD1 319) chain P residue 359 type sequence S description BINDING SITE FOR RESIDUE MG P 9436 source : SD2 320) chain P residue 361 type sequence L description BINDING SITE FOR RESIDUE MG P 9436 source : SD2 321) chain P residue 362 type sequence S description BINDING SITE FOR RESIDUE MG P 9436 source : SD2 322) chain N residue 58 type BINDING sequence C description BINDING => ECO:0000255|HAMAP-Rule:MF_01322 source Swiss-Prot : SWS_FT_FI1 323) chain N residue 60 type BINDING sequence C description BINDING => ECO:0000255|HAMAP-Rule:MF_01322 source Swiss-Prot : SWS_FT_FI1 324) chain N residue 73 type BINDING sequence C description BINDING => ECO:0000255|HAMAP-Rule:MF_01322 source Swiss-Prot : SWS_FT_FI1 325) chain N residue 76 type BINDING sequence C description BINDING => ECO:0000255|HAMAP-Rule:MF_01322 source Swiss-Prot : SWS_FT_FI1 326) chain N residue 739 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_01322 source Swiss-Prot : SWS_FT_FI1 327) chain N residue 741 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_01322 source Swiss-Prot : SWS_FT_FI1 328) chain N residue 743 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_01322 source Swiss-Prot : SWS_FT_FI1 329) chain N residue 1112 type BINDING sequence C description BINDING => ECO:0000255|HAMAP-Rule:MF_01322 source Swiss-Prot : SWS_FT_FI1 330) chain N residue 1194 type BINDING sequence C description BINDING => ECO:0000255|HAMAP-Rule:MF_01322 source Swiss-Prot : SWS_FT_FI1 331) chain N residue 1201 type BINDING sequence C description BINDING => ECO:0000255|HAMAP-Rule:MF_01322 source Swiss-Prot : SWS_FT_FI1 332) chain N residue 1204 type BINDING sequence C description BINDING => ECO:0000255|HAMAP-Rule:MF_01322 source Swiss-Prot : SWS_FT_FI1

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