eF-site ID 2a69-K PDB Code 2a69 Chain K click to enlarge Title Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin Classification TRANSFERASE Compound DNA-directed RNA polymerase alpha chain Source ORGANISM_SCIENTIFIC: Thermus thermophilus; Sequence K:  MLDSKLKAPVFTVRTQGREYGEFVLEPLERGFGVTLGNPL RRILLSSIPGTAVTSVYIEDVLHEFSTIPGVKEDVVEIIL NLKELVVRFLNPSLQTVTLLLKAEGPKEVKARDFLPVADV EIMNPDLHIATLEEGGRLNMEVRVDRGVGYVPAEKHGIKD RINAIPVDAVFSPVRRVAFQVEDTRLGQRTDLDKLTLRIW TDGSVTPLEALNQAVEILREHLTYFSNPQ Description Functional site 1) chain K residue 58 type sequence I description BINDING SITE FOR RESIDUE MG K 9180 source : XC9 2) chain K residue 59 type sequence E description BINDING SITE FOR RESIDUE MG K 9180 source : XC9 3) chain K residue 60 type sequence D description BINDING SITE FOR RESIDUE MG K 9180 source : XC9 4) chain K residue 139 type sequence N description BINDING SITE FOR RESIDUE MG K 9180 source : XC9 5) chain K residue 51 type sequence T description BINDING SITE FOR RESIDUE MG K 9188 source : YC1 6) chain K residue 170 type sequence V description BINDING SITE FOR RESIDUE MG K 9188 source : YC1 7) chain K residue 13 type sequence V description BINDING SITE FOR RESIDUE MG K 9191 source : YC2 8) chain K residue 57 type sequence Y description BINDING SITE FOR RESIDUE MG K 9213 source : YC3 9) chain K residue 141 type sequence E description BINDING SITE FOR RESIDUE MG K 9213 source : YC3 10) chain K residue 160 type sequence D description BINDING SITE FOR RESIDUE MG K 9213 source : YC3 11) chain K residue 161 type sequence R description BINDING SITE FOR RESIDUE MG K 9213 source : YC3 12) chain K residue 7 type sequence K description BINDING SITE FOR RESIDUE MG K 9223 source : YC4 13) chain K residue 27 type sequence P description BINDING SITE FOR RESIDUE MG K 9223 source : YC4 14) chain K residue 28 type sequence L description BINDING SITE FOR RESIDUE MG K 9223 source : YC4 15) chain K residue 118 type sequence A description BINDING SITE FOR RESIDUE MG K 9244 source : YC5 16) chain K residue 119 type sequence D description BINDING SITE FOR RESIDUE MG K 9244 source : YC5 17) chain K residue 137 type sequence R description BINDING SITE FOR RESIDUE MG K 9251 source : YC6 18) chain K residue 139 type sequence N description BINDING SITE FOR RESIDUE MG K 9251 source : YC6 19) chain K residue 95 type sequence Q description BINDING SITE FOR RESIDUE MG K 9257 source : YC7 20) chain K residue 60 type sequence D description BINDING SITE FOR RESIDUE MG K 9264 source : YC8 21) chain K residue 137 type sequence R description BINDING SITE FOR RESIDUE MG K 9264 source : YC8 22) chain K residue 16 type sequence Q description BINDING SITE FOR RESIDUE MG K 9290 source : YC9 23) chain K residue 52 type sequence A description BINDING SITE FOR RESIDUE MG K 9410 source : ZC2 24) chain K residue 54 type sequence T description BINDING SITE FOR RESIDUE MG K 9410 source : ZC2 25) chain K residue 171 type sequence F description BINDING SITE FOR RESIDUE MG K 9410 source : ZC2

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