eF-site ID 2a68-O
PDB Code 2a68
Chain O

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Title Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin
Classification TRANSFERASE
Compound DNA-directed RNA polymerase alpha chain
Source ORGANISM_SCIENTIFIC: Thermus thermophilus;
Sequence O:  AEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHGFKNTVLE
PEERPKMQTLEGLFDDPNAETWAMKELLTGRLVFGENLVP
EDRLQKEMERIYPGE
Description


Functional site

1) chain O
residue 50
type
sequence T
description BINDING SITE FOR RESIDUE MG O 9209
source : VD1

2) chain O
residue 94
type
sequence P
description BINDING SITE FOR RESIDUE MG O 9231
source : VD2

3) chain O
residue 4
type
sequence P
description BINDING SITE FOR RESIDUE MG O 9337
source : VD3

4) chain O
residue 42
type
sequence P
description BINDING SITE FOR RESIDUE MG O 9355
source : VD4

5) chain O
residue 91
type
sequence R
description BINDING SITE FOR RESIDUE MG O 9359
source : VD5

6) chain O
residue 41
type
sequence E
description BINDING SITE FOR RESIDUE MG O 9362
source : VD6

7) chain O
residue 42
type
sequence P
description BINDING SITE FOR RESIDUE MG O 9362
source : VD6


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