|
|
eF-site ID
|
2a68-E |
|
PDB Code
|
2a68 |
|
Chain
|
E |
|
click to enlarge
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Title
|
Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin |
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Classification
|
TRANSFERASE |
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Compound
|
DNA-directed RNA polymerase alpha chain |
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Source
|
ORGANISM_SCIENTIFIC: Thermus thermophilus; |
|
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Sequence
|
E: |
AEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHGFKNTVLE
PEERPKMQTLEGLFDDPNAETWAMKELLTGRLVFGENLVP
EDRLQKEMERIYPGE
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Description
|
|
Functional site
|
|
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1)
|
chain |
E |
| residue |
51 |
| type |
|
| sequence |
L
|
| description |
BINDING SITE FOR RESIDUE MG E 9115
|
| source |
: YC3
|
|
|
2)
|
chain |
E |
| residue |
45 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE MG E 9131
|
| source |
: YC4
|
|
|
3)
|
chain |
E |
| residue |
50 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE MG E 9184
|
| source |
: YC5
|
|
|
|