eF-site ID 2a68-A PDB Code 2a68 Chain A click to enlarge Title Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin Classification TRANSFERASE Compound DNA-directed RNA polymerase alpha chain Source ORGANISM_SCIENTIFIC: Thermus thermophilus; Sequence A:  MLDSKLKAPVFTVRTQGREYGEFVLEPLERGFGVTLGNPL RRILLSSIPGTAVTSVYIEDVLHEFSTIPGVKEDVVEIIL NLKELVVRFLNPSLQTVTLLLKAEGPKEVKARDFLPVADV EIMNPDLHIATLEEGGRLNMEVRVDRGVGYVPAEKHGIKD RINAIPVDAVFSPVRRVAFQVEDTRLGQRTDLDKLTLRIW TDGSVTPLEALNQAVEILREHLTYFSNPQ Description Functional site 1) chain A residue 170 type sequence V description BINDING SITE FOR RESIDUE MG A 9001 source : AC1 2) chain A residue 172 type sequence S description BINDING SITE FOR RESIDUE MG A 9001 source : AC1 3) chain A residue 89 type sequence F description BINDING SITE FOR RESIDUE MG A 9018 source : AC2 4) chain A residue 146 type sequence R description BINDING SITE FOR RESIDUE MG A 9018 source : AC2 5) chain A residue 105 type sequence G description BINDING SITE FOR RESIDUE MG A 9024 source : AC3 6) chain A residue 106 type sequence P description BINDING SITE FOR RESIDUE MG A 9024 source : AC3 7) chain A residue 132 type sequence L description BINDING SITE FOR RESIDUE MG A 9024 source : AC3 8) chain A residue 133 type sequence E description BINDING SITE FOR RESIDUE MG A 9024 source : AC3 9) chain A residue 134 type sequence E description BINDING SITE FOR RESIDUE MG A 9024 source : AC3 10) chain A residue 135 type sequence G description BINDING SITE FOR RESIDUE MG A 9024 source : AC3 11) chain A residue 136 type sequence G description BINDING SITE FOR RESIDUE MG A 9024 source : AC3 12) chain A residue 227 type sequence N description BINDING SITE FOR RESIDUE MG A 9062 source : AC5 13) chain A residue 208 type sequence L description BINDING SITE FOR RESIDUE MG A 9097 source : AC6 14) chain A residue 176 type sequence R description BINDING SITE FOR RESIDUE MG A 9102 source : AC7 15) chain A residue 176 type sequence R description BINDING SITE FOR RESIDUE MG A 9107 source : AC8 16) chain A residue 213 type sequence Q description BINDING SITE FOR RESIDUE MG A 9109 source : AC9 17) chain A residue 229 type sequence Q description BINDING SITE FOR RESIDUE MG A 9126 source : BC3 18) chain A residue 66 type sequence S description BINDING SITE FOR RESIDUE MG A 9139 source : BC4 19) chain A residue 67 type sequence T description BINDING SITE FOR RESIDUE MG A 9139 source : BC4 20) chain A residue 16 type sequence Q description BINDING SITE FOR RESIDUE MG A 9173 source : BC7 21) chain A residue 176 type sequence R description BINDING SITE FOR RESIDUE MG A 9178 source : BC8 22) chain A residue 200 type sequence W description BINDING SITE FOR RESIDUE MG A 9178 source : BC8 23) chain A residue 186 type sequence L description BINDING SITE FOR RESIDUE MG A 9200 source : CC1 24) chain A residue 80 type sequence L description BINDING SITE FOR RESIDUE MG A 9411 source : CC3 25) chain A residue 83 type sequence K description BINDING SITE FOR RESIDUE MG A 9411 source : CC3 26) chain A residue 84 type sequence E description BINDING SITE FOR RESIDUE MG A 9411 source : CC3 27) chain A residue 137 type sequence R description BINDING SITE FOR RESIDUE MG A 9413 source : CC5 28) chain A residue 20 type sequence Y description BINDING SITE FOR RESIDUE MG C 9007 source : FC4 29) chain A residue 22 type sequence E description BINDING SITE FOR RESIDUE MG C 9007 source : FC4 30) chain A residue 122 type sequence I description BINDING SITE FOR RESIDUE MG D 9069 source : PC7

Display surface Download Links