|
|
eF-site ID
|
2a4q-C |
|
PDB Code
|
2a4q |
|
Chain
|
C |
|
click to enlarge
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|
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Title
|
HCV NS3 protease with NS4a peptide and a covalently bound macrocyclic ketoamide compound. |
|
Classification
|
VIRAL PROTEIN |
|
Compound
|
NS3 protease/helicase' |
|
Source
|
Hepatitis C virus (O39914_9HEPC) |
|
|
Sequence
|
C: |
VEGEVQIVSTATQTFLATCINGVCWTVYHGAGTRTIASPK
GPVIQMYTNVDQDLVGWPAPQGSRSLTPCTCGSSDLYLVT
RHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAG
HAVGLFRAAVCTRGVAKAVDFIPVENLETTM
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
97 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN C 302
|
| source |
: AC2
|
|
|
2)
|
chain |
C |
| residue |
99 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN C 302
|
| source |
: AC2
|
|
|
3)
|
chain |
C |
| residue |
145 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN C 302
|
| source |
: AC2
|
|
|
|