|
|
eF-site ID
|
2a25-A |
|
PDB Code
|
2a25 |
|
Chain
|
A |
|
click to enlarge
|
|
|
Title
|
Crystal structure of Siah1 SBD bound to the peptide EKPAAVVAPITTG from SIP |
|
Classification
|
LIGASE |
|
Compound
|
Ubiquitin ligase SIAH1 |
|
Source
|
Homo sapiens (Human) (CYBP_HUMAN) |
|
|
Sequence
|
A: |
PYSCPCPSCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFL
ATDINVDWVMMQSCFGFHFMLVLEKQQQFFAIVQLIGTRK
QAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDC
LVFDTSIAQLFAENGNLGINVTISMC
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
128 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN A 601
|
| source |
: AC1
|
|
|
2)
|
chain |
A |
| residue |
135 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN A 601
|
| source |
: AC1
|
|
|
3)
|
chain |
A |
| residue |
147 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN A 601
|
| source |
: AC1
|
|
|
4)
|
chain |
A |
| residue |
152 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN A 601
|
| source |
: AC1
|
|
|
5)
|
chain |
A |
| residue |
128 |
| type |
BINDING |
| sequence |
C
|
| description |
BINDING => ECO:0000269|PubMed:16085652, ECO:0000269|PubMed:28546513, ECO:0007744|PDB:2A25, ECO:0007744|PDB:5WZZ
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
6)
|
chain |
A |
| residue |
135 |
| type |
BINDING |
| sequence |
C
|
| description |
BINDING => ECO:0000269|PubMed:16085652, ECO:0000269|PubMed:28546513, ECO:0007744|PDB:2A25, ECO:0007744|PDB:5WZZ
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
7)
|
chain |
A |
| residue |
147 |
| type |
BINDING |
| sequence |
H
|
| description |
BINDING => ECO:0000269|PubMed:16085652, ECO:0000269|PubMed:28546513, ECO:0007744|PDB:2A25, ECO:0007744|PDB:5WZZ
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
8)
|
chain |
A |
| residue |
152 |
| type |
BINDING |
| sequence |
H
|
| description |
BINDING => ECO:0000269|PubMed:16085652, ECO:0000269|PubMed:28546513, ECO:0007744|PDB:2A25, ECO:0007744|PDB:5WZZ
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|