eF-site ID 1zm7-A
PDB Code 1zm7
Chain A

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Title Crystal structure of D. melanogaster deoxyribonucleoside kinase mutant N64D in complex with dTTP
Classification TRANSFERASE
Compound Deoxynucleoside kinase
Source Drosophila melanogaster (Fruit fly) (DNK_DROME)
Sequence A:  TKYAEGTQPFTVLIEGNIGSGKTTYLNHFEKYKNDICLLT
EPVEKWRNVNGVDLLELMYKDPKKWAMPFQSYVTLTMLQS
HTAPTNKKLKIMERSIFSARYCFVENMRRNGSLEQGMYNT
LEEWYKFIEESIHVQADLIIYLRTSPEVAYERIRQRARSE
ESCVPLKYLQELHELHEDWLIHQRRPQSCKVLVLDAD
Description


Functional site

1) chain A
residue 29
type
sequence I
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

2) chain A
residue 30
type
sequence G
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

3) chain A
residue 31
type
sequence S
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

4) chain A
residue 32
type
sequence G
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

5) chain A
residue 33
type
sequence K
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

6) chain A
residue 34
type
sequence T
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

7) chain A
residue 52
type
sequence E
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

8) chain A
residue 57
type
sequence W
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

9) chain A
residue 66
type
sequence L
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

10) chain A
residue 69
type
sequence M
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

11) chain A
residue 70
type
sequence Y
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

12) chain A
residue 80
type
sequence F
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

13) chain A
residue 81
type
sequence Q
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

14) chain A
residue 84
type
sequence V
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

15) chain A
residue 104
type
sequence E
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

16) chain A
residue 105
type
sequence R
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

17) chain A
residue 110
type
sequence A
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

18) chain A
residue 114
type
sequence F
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

19) chain A
residue 118
type
sequence M
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

20) chain A
residue 167
type
sequence R
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

21) chain A
residue 169
type
sequence R
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

22) chain A
residue 172
type
sequence E
description BINDING SITE FOR RESIDUE TTP A 300
source : AC2

23) chain A
residue 104
type ACT_SITE
sequence E
description Proton acceptor => ECO:0000255
source Swiss-Prot : SWS_FT_FI1

24) chain A
residue 27
type BINDING
sequence G
description BINDING => ECO:0000250
source Swiss-Prot : SWS_FT_FI2

25) chain A
residue 52
type BINDING
sequence E
description
source Swiss-Prot : SWS_FT_FI3

26) chain A
residue 70
type BINDING
sequence Y
description
source Swiss-Prot : SWS_FT_FI3

27) chain A
residue 81
type BINDING
sequence Q
description
source Swiss-Prot : SWS_FT_FI3

28) chain A
residue 105
type BINDING
sequence R
description
source Swiss-Prot : SWS_FT_FI3

29) chain A
residue 172
type BINDING
sequence E
description
source Swiss-Prot : SWS_FT_FI3


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