eF-site ID 1z8y-S
PDB Code 1z8y
Chain S

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Title Mapping the E2 Glycoprotein of Alphaviruses
Classification VIRUS
Compound Spike glycoprotein E1
Source ORGANISM_SCIENTIFIC: Sindbis virus;
Sequence S:  RLFDVKNEDGDVIGHALAMEGKVMKPLHVKGTIDHPVLSK
LKFTKSSAYDMEFAQLPVNMRSEAFTYTSEHPEGFYNWHH
GAVQYSGGRFTIPRGVGGRGDSGRPIMDNSGRVVAIVLGG
ADEGTRTALSVVTWNSKGKTIKTTPEGTEEW
Description (1)  Spike glycoprotein E1, Spike glycoprotein E2, Capsid protein C (E.C.3.4.21.-)


Functional site

1) chain S
residue 189
type SITE
sequence Y
description Involved in dimerization of the capsid protein => ECO:0000250|UniProtKB:Q86925
source Swiss-Prot : SWS_FT_FI2

2) chain S
residue 222
type SITE
sequence N
description Involved in dimerization of the capsid protein => ECO:0000250|UniProtKB:Q86925
source Swiss-Prot : SWS_FT_FI2

3) chain S
residue 264
type SITE
sequence W
description Cleavage; by autolysis => ECO:0000250|UniProtKB:P03315
source Swiss-Prot : SWS_FT_FI3

4) chain S
residue 141
type ACT_SITE
sequence H
description Charge relay system => ECO:0000255|PROSITE-ProRule:PRU01027, ECO:0000269|PubMed:1944569
source Swiss-Prot : SWS_FT_FI1

5) chain S
residue 163
type ACT_SITE
sequence D
description Charge relay system => ECO:0000255|PROSITE-ProRule:PRU01027, ECO:0000269|PubMed:1944569
source Swiss-Prot : SWS_FT_FI1

6) chain S
residue 215
type ACT_SITE
sequence S
description Charge relay system => ECO:0000255|PROSITE-ProRule:PRU01027, ECO:0000269|PubMed:1944569
source Swiss-Prot : SWS_FT_FI1


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