eF-site ID 1z6t-C PDB Code 1z6t Chain C click to enlarge Title Structure of the apoptotic protease-activating factor 1 bound to ADP Classification APOPTOSIS Compound Apoptotic protease activating factor 1 Source Homo sapiens (Human) (APAF_HUMAN) Sequence C:  MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEE EKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGY KDLAALLHDGIPVVSSSSGKDSVSGITSYVRTVLCEGGVP QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGK SVLAAEAVRDHSLLEGCFPGGVHWVSVGKQDKSGLLMKLQ NLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVV PVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKGS PLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYD YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVL CILWDMETEEVEDILQEFVNKSLLFCDRNGKSFRYYLHDL QVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDC MYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPA HLIHEFVEYRHILDEKDCAVSENFQEFLSLNGHLLGRQPF PNIVQLGLCEPETSEVYQQAKLQAKQ Description Functional site 1) chain C residue 125 type sequence V description BINDING SITE FOR RESIDUE ADP C 902 source : AC3 2) chain C residue 126 type sequence F description BINDING SITE FOR RESIDUE ADP C 902 source : AC3 3) chain C residue 127 type sequence V description BINDING SITE FOR RESIDUE ADP C 902 source : AC3 4) chain C residue 157 type sequence G description BINDING SITE FOR RESIDUE ADP C 902 source : AC3 5) chain C residue 158 type sequence C description BINDING SITE FOR RESIDUE ADP C 902 source : AC3 6) chain C residue 159 type sequence G description BINDING SITE FOR RESIDUE ADP C 902 source : AC3 7) chain C residue 160 type sequence K description BINDING SITE FOR RESIDUE ADP C 902 source : AC3 8) chain C residue 161 type sequence S description BINDING SITE FOR RESIDUE ADP C 902 source : AC3 9) chain C residue 162 type sequence V description BINDING SITE FOR RESIDUE ADP C 902 source : AC3 10) chain C residue 321 type sequence P description BINDING SITE FOR RESIDUE ADP C 902 source : AC3 11) chain C residue 322 type sequence L description BINDING SITE FOR RESIDUE ADP C 902 source : AC3 12) chain C residue 425 type sequence F description BINDING SITE FOR RESIDUE ADP C 902 source : AC3 13) chain C residue 438 type sequence H description BINDING SITE FOR RESIDUE ADP C 902 source : AC3 14) chain C residue 154 type BINDING sequence G description BINDING => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 15) chain C residue 265 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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