eF-site ID 1z6t-B PDB Code 1z6t Chain B click to enlarge Title Structure of the apoptotic protease-activating factor 1 bound to ADP Classification APOPTOSIS Compound Apoptotic protease activating factor 1 Source Homo sapiens (Human) (APAF_HUMAN) Sequence B:  MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEE EKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGY KDLAALLHDGIPVVSSSSGKDSVSGITSYVRTVLCEGGVP QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGK SVLAAEAVRDHSLLEGCFPGGVHWVSVGKQDKSGLLMKLQ NLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL ILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVV PVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKGS PLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYD YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVL CILWDMETEEVEDILQEFVNKSLLFCDRNGKSFRYYLHDL QVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDC MYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPA HLIHEFVEYRHILDEKDCAVSENFQEFLSLNGHLLGRQPF PNIVQLGLCEPETSEVYQQAKLQAKQ Description Functional site 1) chain B residue 125 type sequence V description BINDING SITE FOR RESIDUE ADP B 901 source : AC2 2) chain B residue 126 type sequence F description BINDING SITE FOR RESIDUE ADP B 901 source : AC2 3) chain B residue 127 type sequence V description BINDING SITE FOR RESIDUE ADP B 901 source : AC2 4) chain B residue 157 type sequence G description BINDING SITE FOR RESIDUE ADP B 901 source : AC2 5) chain B residue 158 type sequence C description BINDING SITE FOR RESIDUE ADP B 901 source : AC2 6) chain B residue 159 type sequence G description BINDING SITE FOR RESIDUE ADP B 901 source : AC2 7) chain B residue 160 type sequence K description BINDING SITE FOR RESIDUE ADP B 901 source : AC2 8) chain B residue 161 type sequence S description BINDING SITE FOR RESIDUE ADP B 901 source : AC2 9) chain B residue 162 type sequence V description BINDING SITE FOR RESIDUE ADP B 901 source : AC2 10) chain B residue 321 type sequence P description BINDING SITE FOR RESIDUE ADP B 901 source : AC2 11) chain B residue 322 type sequence L description BINDING SITE FOR RESIDUE ADP B 901 source : AC2 12) chain B residue 425 type sequence F description BINDING SITE FOR RESIDUE ADP B 901 source : AC2 13) chain B residue 438 type sequence H description BINDING SITE FOR RESIDUE ADP B 901 source : AC2 14) chain B residue 154 type BINDING sequence G description BINDING => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 15) chain B residue 265 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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