eF-site ID 1z6t-A PDB Code 1z6t Chain A click to enlarge Title Structure of the apoptotic protease-activating factor 1 bound to ADP Classification APOPTOSIS Compound Apoptotic protease activating factor 1 Source Homo sapiens (Human) (APAF_HUMAN) Sequence A:  MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEE EKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGY KDLAALLHDGIPVVGITSYVRTVLCEGGVPQRPVVFVTRK KLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRD HSLLEGCFPGGVHWVSVGKQDKSGLLMKLQNLCTRLDQDE SFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWV LKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEK GLEILSLFVNMKKADLPEQAHSIIKECKGSPLVVSLIGAL LRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSI SVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEE VEDILQEFVNKSLLFCDRNGKSFRYYLHDLQVDFLTEKNC SQLQDLHKKIITQFQRYHQPHTLSPDQEDCMYWYNFLAYH MASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYR HILDEKDCAVSENFQEFLSLNGHLLGRQPFPNIVQLGLCE PETSEVYQQAKLQAKQ Description Functional site 1) chain A residue 125 type sequence V description BINDING SITE FOR RESIDUE ADP A 900 source : AC1 2) chain A residue 126 type sequence F description BINDING SITE FOR RESIDUE ADP A 900 source : AC1 3) chain A residue 127 type sequence V description BINDING SITE FOR RESIDUE ADP A 900 source : AC1 4) chain A residue 129 type sequence R description BINDING SITE FOR RESIDUE ADP A 900 source : AC1 5) chain A residue 157 type sequence G description BINDING SITE FOR RESIDUE ADP A 900 source : AC1 6) chain A residue 158 type sequence C description BINDING SITE FOR RESIDUE ADP A 900 source : AC1 7) chain A residue 159 type sequence G description BINDING SITE FOR RESIDUE ADP A 900 source : AC1 8) chain A residue 160 type sequence K description BINDING SITE FOR RESIDUE ADP A 900 source : AC1 9) chain A residue 161 type sequence S description BINDING SITE FOR RESIDUE ADP A 900 source : AC1 10) chain A residue 162 type sequence V description BINDING SITE FOR RESIDUE ADP A 900 source : AC1 11) chain A residue 321 type sequence P description BINDING SITE FOR RESIDUE ADP A 900 source : AC1 12) chain A residue 322 type sequence L description BINDING SITE FOR RESIDUE ADP A 900 source : AC1 13) chain A residue 425 type sequence F description BINDING SITE FOR RESIDUE ADP A 900 source : AC1 14) chain A residue 438 type sequence H description BINDING SITE FOR RESIDUE ADP A 900 source : AC1 15) chain A residue 154 type BINDING sequence G description BINDING => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 16) chain A residue 265 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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