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eF-site ID
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1z6j-T |
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PDB Code
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1z6j |
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Chain
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T |
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click to enlarge
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Title
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Crystal Structure of a ternary complex of Factor VIIa/Tissue Factor/Pyrazinone Inhibitor |
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Classification
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HYDROLASE |
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Compound
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Coagulation factor VII |
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Source
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(TF_HUMAN) |
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Sequence
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T: |
SGTTNTVAAYNLTWKSTNFKTILEWEPKPVNQVYTVQIST
KSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPA
GNVESTEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVN
VTVEDERTLVRRNNTFLSLRDVFGKDLIYTLYYWKSSSSG
KKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTD
SPVECMG
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Description
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(1) |
Blood coagulation factor VIIa (E.C.3.4.21.21), Soluble tissue factor, Pyrazinone inhibitor with benzamidine as the P1 warhead
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Functional site
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1)
|
chain |
T |
| residue |
45-62 |
| type |
prosite |
| sequence |
WKSKCFYTTDTECDLTDE
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| description |
TISSUE_FACTOR Tissue factor signature. WKsKCfyTtDTECDLTDE
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| source |
prosite : PS00621
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2)
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chain |
T |
| residue |
124 |
| type |
CARBOHYD |
| sequence |
N
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| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
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| source |
Swiss-Prot : SWS_FT_FI1
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3)
|
chain |
T |
| residue |
137 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
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