eF-site ID 1z4u-A PDB Code 1z4u Chain A click to enlarge Title hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00799585 Classification TRANSFERASE Compound HCV NS5B POLYMERASE Source (O93077_9HEPC) Sequence A:  MSMSYTWTGALITPCAAEESKLPINALSNSLLRHHNLVYS TTSRSASLRQKKVTFDRLQVLDDHYRDVLKEMKAKASTVK AKLLSVEEACKLTPPHSAKSKFGYGAKDVRSLSSRAVNHI RSVWKDLLEDTDTPIQTTIMAKNEVFCVQPEKGGRKPARL IVFPDLGVRVCEKMALYDVVSTLPQAVMGSSYGFQYSPKQ RVEFLVNTWKAKKCPMGFSYDTRCFDSTVTENDIRVEESI YQCCDLAPEARQAIRSLTERLYVGGPMTNSKGQNCGYRRC RASGVLTTSCGNTLTCYLKAAAACRAAKLQDCTMLVNGDD LVVICESAGTQEDAASLRVFTEAMTRYSAPPGDPPQPEYD LELITSCSSNVSVAHDASGKRVYYLTRDPTVPLARAAWET ARHTPVNSWLGNIIMYAPTLWARMILMTHFFSILLAQEQL EKALDCQIYGACYSIEPLDLPQIIERLHGLSAFSLHSYSP GEINRVASCLRKLGVPPLRVWRHRARSVRAKLLSQGGRAA ICGKYLFNWAVRTKLKLTPIPAASRLLLSGWFVAGYSGGD IYHS Description Functional site 1) chain A residue 480 type sequence G description BINDING SITE FOR RESIDUE CL A 701 source : AC1 2) chain A residue 480 type sequence G description BINDING SITE FOR RESIDUE CL A 701 source : AC1 3) chain A residue 480 type sequence G description BINDING SITE FOR RESIDUE PO4 A 702 source : AC2 4) chain A residue 484 type sequence R description BINDING SITE FOR RESIDUE PO4 A 702 source : AC2 5) chain A residue 200 type sequence R description BINDING SITE FOR RESIDUE PH9 A 600 source : AC3 6) chain A residue 316 type sequence N description BINDING SITE FOR RESIDUE PH9 A 600 source : AC3 7) chain A residue 366 type sequence C description BINDING SITE FOR RESIDUE PH9 A 600 source : AC3 8) chain A residue 368 type sequence S description BINDING SITE FOR RESIDUE PH9 A 600 source : AC3 9) chain A residue 384 type sequence L description BINDING SITE FOR RESIDUE PH9 A 600 source : AC3 10) chain A residue 410 type sequence G description BINDING SITE FOR RESIDUE PH9 A 600 source : AC3 11) chain A residue 411 type sequence N description BINDING SITE FOR RESIDUE PH9 A 600 source : AC3 12) chain A residue 414 type sequence M description BINDING SITE FOR RESIDUE PH9 A 600 source : AC3 13) chain A residue 415 type sequence Y description BINDING SITE FOR RESIDUE PH9 A 600 source : AC3 14) chain A residue 446 type sequence Q description BINDING SITE FOR RESIDUE PH9 A 600 source : AC3 15) chain A residue 447 type sequence I description BINDING SITE FOR RESIDUE PH9 A 600 source : AC3 16) chain A residue 448 type sequence Y description BINDING SITE FOR RESIDUE PH9 A 600 source : AC3 17) chain A residue 556 type sequence S description BINDING SITE FOR RESIDUE PH9 A 600 source : AC3 18) chain A residue 319 type sequence D description BINDING SITE FOR RESIDUE GOL A 602 source : AC4 19) chain A residue 366 type sequence C description BINDING SITE FOR RESIDUE GOL A 602 source : AC4 20) chain A residue 367 type sequence S description BINDING SITE FOR RESIDUE GOL A 602 source : AC4 21) chain A residue 213 type sequence C description BINDING SITE FOR RESIDUE GOL A 604 source : AC5 22) chain A residue 329 type sequence T description BINDING SITE FOR RESIDUE GOL A 604 source : AC5 23) chain A residue 358 type sequence Y description BINDING SITE FOR RESIDUE GOL A 604 source : AC5 24) chain A residue 359 type sequence D description BINDING SITE FOR RESIDUE GOL A 605 source : AC6 25) chain A residue 419 type sequence L description BINDING SITE FOR RESIDUE GOL A 605 source : AC6 26) chain A residue 482 type sequence I description BINDING SITE FOR RESIDUE GOL A 605 source : AC6 27) chain A residue 497 type sequence L description BINDING SITE FOR RESIDUE GOL A 605 source : AC6

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