eF-site ID 1yve-L PDB Code 1yve Chain L click to enlarge Title ACETOHYDROXY ACID ISOMEROREDUCTASE COMPLEXED WITH NADPH, MAGNESIUM AND INHIBITOR IPOHA (N-HYDROXY-N-ISOPROPYLOXAMATE) Classification OXIDOREDUCTASE Compound ACETOHYDROXY ACID ISOMEROREDUCTASE Source null (ILV5_SPIOL) Sequence L:  ATTFDFDSSVFKKEKVTLSGHDEYIVRGGRNLFPLLPDAF KGIKQIGVIGWGSQAPAQAQNLKDSLTEAKSDVVVKIGLR KGSNSFAEARAAGFSEENGTLGDMWETISGSDLVLLLISD SAQADNYEKVFSHMKPNSILGLSHGFLLGHLQSLGQDFPK NISVIAVCPKGMGPSVRRLYVQGKEVNGAGINSSFAVHQD VDGRATDVALGWSIALGSPFTFATTLEQEYKSDIFGERGI LLGAVHGIVECLFRRYTESGMSEDLAYKNTVECITGVISK TISTKGMLALYNSLSEEGKKDFQAAYSASYYPSMDILYEC YEDVASGSEIRSVVLAGRRFYEKEGLPAFPMGKIDQTRMW KVGEKVRSVRPAGDLGPLYPFTAGVYVALMMAQIEILRKK GHSYSEIINESVIEAVDSLNPFMHARGVSFMVDNCSTTAR LGSRKWAPRFDYILSQQALVAVDNGAPINQDLISNFLSDP VHEAIGVCAQLRPSVDISVTADADFVRPELRQA Description Functional site 1) chain L residue 315 type sequence D description BINDING SITE FOR RESIDUE MG L 601 source : BC1 2) chain L residue 319 type sequence E description BINDING SITE FOR RESIDUE MG L 601 source : BC1 3) chain L residue 315 type sequence D description BINDING SITE FOR RESIDUE MG L 602 source : BC2 4) chain L residue 132 type sequence G description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 5) chain L residue 133 type sequence W description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 6) chain L residue 134 type sequence G description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 7) chain L residue 135 type sequence S description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 8) chain L residue 136 type sequence Q description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 9) chain L residue 162 type sequence R description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 10) chain L residue 165 type sequence S description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 11) chain L residue 167 type sequence S description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 12) chain L residue 199 type sequence L description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 13) chain L residue 200 type sequence I description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 14) chain L residue 201 type sequence S description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 15) chain L residue 202 type sequence D description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 16) chain L residue 204 type sequence A description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 17) chain L residue 205 type sequence Q description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 18) chain L residue 225 type sequence S description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 19) chain L residue 226 type sequence H description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 20) chain L residue 251 type sequence P description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 21) chain L residue 253 type sequence G description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 22) chain L residue 254 type sequence M description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 23) chain L residue 255 type sequence G description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 24) chain L residue 517 type sequence C description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 25) chain L residue 518 type sequence S description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 26) chain L residue 519 type sequence T description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 27) chain L residue 589 type sequence R description BINDING SITE FOR RESIDUE NDP K 605 source : BC7 28) chain L residue 253 type sequence G description BINDING SITE FOR RESIDUE HIO L 603 source : CC1 29) chain L residue 254 type sequence M description BINDING SITE FOR RESIDUE HIO L 603 source : CC1 30) chain L residue 315 type sequence D description BINDING SITE FOR RESIDUE HIO L 603 source : CC1 31) chain L residue 319 type sequence E description BINDING SITE FOR RESIDUE HIO L 603 source : CC1 32) chain L residue 496 type sequence E description BINDING SITE FOR RESIDUE HIO L 603 source : CC1 33) chain L residue 501 type sequence L description BINDING SITE FOR RESIDUE HIO L 603 source : CC1 34) chain L residue 517 type sequence C description BINDING SITE FOR RESIDUE HIO L 603 source : CC1 35) chain L residue 518 type sequence S description BINDING SITE FOR RESIDUE HIO L 603 source : CC1 36) chain L residue 521 type sequence A description BINDING SITE FOR RESIDUE HIO L 603 source : CC1 37) chain L residue 226 type ACT_SITE sequence H description ACT_SITE => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 38) chain L residue 129 type BINDING sequence G description BINDING => ECO:0000269|PubMed:10739911, ECO:0000269|PubMed:9218783 source Swiss-Prot : SWS_FT_FI2 39) chain L residue 162 type BINDING sequence R description BINDING => ECO:0000269|PubMed:10739911, ECO:0000269|PubMed:9218783 source Swiss-Prot : SWS_FT_FI2 40) chain L residue 201 type BINDING sequence S description BINDING => ECO:0000269|PubMed:10739911, ECO:0000269|PubMed:9218783 source Swiss-Prot : SWS_FT_FI2 41) chain L residue 315 type BINDING sequence D description BINDING => ECO:0000255|PROSITE-ProRule:PRU01198 source Swiss-Prot : SWS_FT_FI3 42) chain L residue 319 type BINDING sequence E description BINDING => ECO:0000255|PROSITE-ProRule:PRU01198 source Swiss-Prot : SWS_FT_FI3 43) chain L residue 492 type BINDING sequence E description BINDING => ECO:0000255|PROSITE-ProRule:PRU01198 source Swiss-Prot : SWS_FT_FI3 44) chain L residue 496 type BINDING sequence E description BINDING => ECO:0000255|PROSITE-ProRule:PRU01198 source Swiss-Prot : SWS_FT_FI3 45) chain L residue 518 type BINDING sequence S description BINDING => ECO:0000255|PROSITE-ProRule:PRU01198 source Swiss-Prot : SWS_FT_FI3 46) chain L residue 252 type catalytic sequence K description 890 source MCSA : MCSA4 47) chain L residue 315 type catalytic sequence D description 890 source MCSA : MCSA4 48) chain L residue 319 type catalytic sequence E description 890 source MCSA : MCSA4

Display surface Download Links