|
|
eF-site ID
|
1yer-A |
|
PDB Code
|
1yer |
|
Chain
|
A |
|
click to enlarge
|
|
|
Title
|
HUMAN HSP90 GELDANAMYCIN-BINDING DOMAIN, "CLOSED" CONFORMATION |
|
Classification
|
CHAPERONE PROTEIN |
|
Compound
|
HEAT SHOCK PROTEIN 90 |
|
Source
|
Homo sapiens (Human) (HS90A_HUMAN) |
|
|
Sequence
|
A: |
VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDAL
DKIRYETLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGI
GMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGV
GFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDT
GEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGY
PITLFVE
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
52 |
| type |
BINDING |
| sequence |
S
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
A |
| residue |
94 |
| type |
BINDING |
| sequence |
T
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
A |
| residue |
139 |
| type |
BINDING |
| sequence |
Y
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
A |
| residue |
113 |
| type |
BINDING |
| sequence |
S
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
A |
| residue |
38-47 |
| type |
prosite |
| sequence |
YSNKEIFLRE
|
| description |
HSP90 Heat shock hsp90 proteins family signature. YsNKEIFLRE
|
| source |
prosite : PS00298
|
|
|
6)
|
chain |
A |
| residue |
59 |
| type |
MOD_RES |
| sequence |
I
|
| description |
N6-acetyllysine => ECO:0000250|UniProtKB:P07901
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
7)
|
chain |
A |
| residue |
85 |
| type |
MOD_RES |
| sequence |
Q
|
| description |
N6-acetyllysine => ECO:0000250|UniProtKB:P07901
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|