|
|
eF-site ID
|
1ydi-A |
|
PDB Code
|
1ydi |
|
Chain
|
A |
|
click to enlarge
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Title
|
Human Vinculin Head Domain (VH1, 1-258) in Complex with Human Alpha-Actinin's Vinculin-Binding Site (Residues 731-760) |
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Classification
|
Cell Adhesion, Structural Protein |
|
Compound
|
vinculin isoform VCL |
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Source
|
null (AAC4_HUMAN) |
|
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Sequence
|
A: |
HHHHHMPVFHTRTIESILEPVAQQISHLVIMHEAIPDLTA
PVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVE
NACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDL
LLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTK
NLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELL
PVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEIN
EIIRVLQLTSWDEDAW
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
162-182 |
| type |
prosite |
| sequence |
KNLGPGMTKMAKMIDERQQEL
|
| description |
VINCULIN_1 Vinculin family talin-binding region signature. KnLgpgMtkMakmideRQQEL
|
| source |
prosite : PS00663
|
|
|
2)
|
chain |
A |
| residue |
97 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0000250|UniProtKB:P85972
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
A |
| residue |
173 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI2
|
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