|
eF-site ID
|
1y8x-A |
PDB Code
|
1y8x |
Chain
|
A |
|
click to enlarge
|
|
Title
|
Structural basis for recruitment of Ubc12 by an E2-binding domain in NEDD8's E1 |
Classification
|
LIGASE |
Compound
|
Ubiquitin-conjugating enzyme E2 M |
Source
|
Homo sapiens (Human) (UBA3_HUMAN) |
|
Sequence
|
A: |
GSXASAAQLRIQKDINELNLPKTCDISFSDPDDLLNFKLV
ICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETXVYHPN
IDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPED
PLNKEAAEVLQNNRRLFEQNVQRSXRGGYIGSTYFERCLK
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
A |
residue |
100-115 |
type |
prosite |
sequence |
YHPNIDLEGNVCLNIL
|
description |
UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNIdle.GnVCLniL
|
source |
prosite : PS00183
|
|
2)
|
chain |
A |
residue |
111 |
type |
ACT_SITE |
sequence |
C
|
description |
Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
3)
|
chain |
A |
residue |
50 |
type |
MOD_RES |
sequence |
S
|
description |
Phosphoserine => ECO:0007744|PubMed:18669648
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
4)
|
chain |
A |
residue |
169 |
type |
MOD_RES |
sequence |
R
|
description |
Omega-N-methylarginine; alternate => ECO:0007744|PubMed:24129315
|
source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|