eF-site ID 1y77-B PDB Code 1y77 Chain B click to enlarge Title Complete RNA Polymerase II elongation complex with substrate analogue GMPCPP Classification TRANSCRIPTION,TRANSFERASE/DNA-RNA HYBRID Compound 5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*T*CP*GP*CP*CP*TP*GP*GP*TP*CP*TP*G)-3' Source ORGANISM_COMMON: baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence B:  DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTL QDIICEDSTLIISFGKIYVTKPMVNESDGVTHALYPQEAR LRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATES DLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFK KAAPSPISHVAEIRSALEKGSRFISTLQVKLYGREGSSAR TIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVND WQMLEMLKPCVEDGFVIQDRETALDFIGKEKRIQYAKDIL QKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQD DRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTV ELAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLN RYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCP AETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGME PLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLR RKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDE SLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYI DAEEEESILIAMQPEDLEPAEADVDPAKRIRVSHHATTFT HCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMG VFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPA GQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSY MDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLI APGVRVSGEDVIIGKTTPISSKRDASTPLRSTENGIVDQV LVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGI TYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLS KVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVM YNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQ VLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLM EASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIY QIHIPYAAKLLFQELMAMNITPRLYTDRSRDF Description Functional site 1) chain B residue 1163 type sequence C description BINDING SITE FOR RESIDUE ZN B 1307 source : AC3 2) chain B residue 1166 type sequence C description BINDING SITE FOR RESIDUE ZN B 1307 source : AC3 3) chain B residue 1182 type sequence C description BINDING SITE FOR RESIDUE ZN B 1307 source : AC3 4) chain B residue 1185 type sequence C description BINDING SITE FOR RESIDUE ZN B 1307 source : AC3 5) chain B residue 837 type catalytic sequence D description 788 source MCSA : MCSA1 6) chain B residue 1185 type BINDING sequence C description source Swiss-Prot : SWS_FT_FI2 7) chain B residue 977-989 type prosite sequence GDKFASRHGQKGT description RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT source prosite : PS01166

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