eF-site ID 1y3a-C PDB Code 1y3a Chain C click to enlarge Title Structure of G-Alpha-I1 bound to a GDP-selective peptide provides insight into guanine nucleotide exchange Classification SIGNALING PROTEIN Compound Guanine nucleotide-binding protein G(i), alpha-1 subunit Source (1Y3A) Sequence C:  VKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVV YSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAMT AELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFD VGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVMNRMHES MKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTIC YPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTHFTCA TDTKNVQFVFDAVTDVII Description Functional site 1) chain C residue 42 type sequence G description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 2) chain C residue 43 type sequence E description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 3) chain C residue 44 type sequence S description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 4) chain C residue 45 type sequence G description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 5) chain C residue 46 type sequence K description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 6) chain C residue 47 type sequence S description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 7) chain C residue 48 type sequence T description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 8) chain C residue 150 type sequence D description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 9) chain C residue 175 type sequence L description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 10) chain C residue 176 type sequence R description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 11) chain C residue 177 type sequence T description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 12) chain C residue 178 type sequence R description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 13) chain C residue 269 type sequence N description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 14) chain C residue 270 type sequence K description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 15) chain C residue 272 type sequence D description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 16) chain C residue 273 type sequence L description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 17) chain C residue 325 type sequence C description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 18) chain C residue 326 type sequence A description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 19) chain C residue 327 type sequence T description BINDING SITE FOR RESIDUE GDP C 357 source : AC3 20) chain C residue 44 type BINDING sequence S description BINDING => ECO:0000269|PubMed:21115486, ECO:0007744|PDB:1KJY, ECO:0007744|PDB:1Y3A, ECO:0007744|PDB:2G83, ECO:0007744|PDB:2GTP, ECO:0007744|PDB:2IK8, ECO:0007744|PDB:2OM2, ECO:0007744|PDB:2XNS, ECO:0007744|PDB:3ONW, ECO:0007744|PDB:3QE0, ECO:0007744|PDB:3QI2, ECO:0007744|PDB:3UMR, ECO:0007744|PDB:3UMS, ECO:0007744|PDB:4G5Q source Swiss-Prot : SWS_FT_FI1 21) chain C residue 270 type BINDING sequence K description BINDING => ECO:0000269|PubMed:21115486, ECO:0007744|PDB:1KJY, ECO:0007744|PDB:1Y3A, ECO:0007744|PDB:2G83, ECO:0007744|PDB:2GTP, ECO:0007744|PDB:2IK8, ECO:0007744|PDB:2OM2, ECO:0007744|PDB:2XNS, ECO:0007744|PDB:3ONW, ECO:0007744|PDB:3QE0, ECO:0007744|PDB:3QI2, ECO:0007744|PDB:3UMR, ECO:0007744|PDB:3UMS, ECO:0007744|PDB:4G5Q source Swiss-Prot : SWS_FT_FI1 22) chain C residue 48 type BINDING sequence T description BINDING => ECO:0000269|PubMed:18434541, ECO:0000269|PubMed:22383884, ECO:0007744|PDB:3QE0 source Swiss-Prot : SWS_FT_FI2 23) chain C residue 182 type BINDING sequence T description BINDING => ECO:0000269|PubMed:18434541, ECO:0000269|PubMed:22383884, ECO:0007744|PDB:3QE0 source Swiss-Prot : SWS_FT_FI2 24) chain C residue 152 type BINDING sequence A description BINDING => ECO:0007744|PDB:1KJY, ECO:0007744|PDB:2OM2, ECO:0007744|PDB:2XNS, ECO:0007744|PDB:3ONW, ECO:0007744|PDB:3QE0, ECO:0007744|PDB:3QI2, ECO:0007744|PDB:4G5Q source Swiss-Prot : SWS_FT_FI3 25) chain C residue 176 type BINDING sequence R description BINDING => ECO:0007744|PDB:1KJY, ECO:0007744|PDB:1Y3A, ECO:0007744|PDB:2G83, ECO:0007744|PDB:2GTP, ECO:0007744|PDB:2IK8, ECO:0007744|PDB:2OM2, ECO:0007744|PDB:2XNS, ECO:0007744|PDB:3ONW, ECO:0007744|PDB:3QE0, ECO:0007744|PDB:3QI2, ECO:0007744|PDB:3UMR, ECO:0007744|PDB:3UMS, ECO:0007744|PDB:4G5Q source Swiss-Prot : SWS_FT_FI4 26) chain C residue 201 type BINDING sequence V description BINDING => ECO:0000269|PubMed:21115486 source Swiss-Prot : SWS_FT_FI5 27) chain C residue 327 type BINDING sequence T description BINDING => ECO:0007744|PDB:1Y3A, ECO:0007744|PDB:2G83, ECO:0007744|PDB:2GTP, ECO:0007744|PDB:2IK8, ECO:0007744|PDB:2OM2, ECO:0007744|PDB:3ONW, ECO:0007744|PDB:3QE0, ECO:0007744|PDB:3QI2, ECO:0007744|PDB:3UMR, ECO:0007744|PDB:3UMS, ECO:0007744|PDB:4G5Q source Swiss-Prot : SWS_FT_FI6 28) chain C residue 179 type MOD_RES sequence V description ADP-ribosylarginine; by cholera toxin => ECO:0000250 source Swiss-Prot : SWS_FT_FI7 29) chain C residue 205 type MOD_RES sequence R description Deamidated glutamine; by Photorhabdus PAU_02230 => ECO:0000269|PubMed:24141704 source Swiss-Prot : SWS_FT_FI8

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