eF-site ID 1xxv-B PDB Code 1xxv Chain B click to enlarge Title Yersinia YopH (residues 163-468) binds phosphonodifluoromethyl-Phe containing hexapeptide at two sites Classification HYDROLASE Compound Protein-tyrosine phosphatase yopH Source Yersinia enterocolitica (1XXV) Sequence B:  SPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKL NRFRDIQCRRQTAVRADLNANYIQVGNTRTIACQYPLQSQ LESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSG TYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISV PVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESK GSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQ LSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLL NS Description Functional site 1) chain B residue 468 type sequence S description BINDING SITE FOR CHAIN D OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC2 2) chain B residue 229 type sequence F description BINDING SITE FOR CHAIN E OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC3 3) chain B residue 230 type sequence R description BINDING SITE FOR CHAIN E OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC3 4) chain B residue 231 type sequence D description BINDING SITE FOR CHAIN E OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC3 5) chain B residue 232 type sequence I description BINDING SITE FOR CHAIN E OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC3 6) chain B residue 356 type sequence D description BINDING SITE FOR CHAIN E OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC3 7) chain B residue 357 type sequence Q description BINDING SITE FOR CHAIN E OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC3 8) chain B residue 403 type sequence C description BINDING SITE FOR CHAIN E OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC3 9) chain B residue 404 type sequence R description BINDING SITE FOR CHAIN E OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC3 10) chain B residue 405 type sequence A description BINDING SITE FOR CHAIN E OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC3 11) chain B residue 406 type sequence G description BINDING SITE FOR CHAIN E OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC3 12) chain B residue 407 type sequence V description BINDING SITE FOR CHAIN E OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC3 13) chain B residue 408 type sequence G description BINDING SITE FOR CHAIN E OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC3 14) chain B residue 409 type sequence R description BINDING SITE FOR CHAIN E OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC3 15) chain B residue 446 type sequence Q description BINDING SITE FOR CHAIN E OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC3 16) chain B residue 278 type sequence R description BINDING SITE FOR CHAIN F OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC4 17) chain B residue 295 type sequence R description BINDING SITE FOR CHAIN F OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC4 18) chain B residue 342 type sequence K description BINDING SITE FOR CHAIN F OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC4 19) chain B residue 343 type sequence T description BINDING SITE FOR CHAIN F OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC4 20) chain B residue 344 type sequence I description BINDING SITE FOR CHAIN F OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC4 21) chain B residue 345 type sequence S description BINDING SITE FOR CHAIN F OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC4 22) chain B residue 386 type sequence K description BINDING SITE FOR CHAIN F OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC4 23) chain B residue 388 type sequence S description BINDING SITE FOR CHAIN F OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC4 24) chain B residue 389 type sequence S description BINDING SITE FOR CHAIN F OF EPIDERMAL GROWTH FACTOR RECEPTOR DERIVED PEPTIDE source : AC4 25) chain B residue 290 type catalytic sequence E description 47 source MCSA : MCSA2 26) chain B residue 354 type catalytic sequence W description 47 source MCSA : MCSA2 27) chain B residue 356 type catalytic sequence D description 47 source MCSA : MCSA2 28) chain B residue 402 type catalytic sequence H description 47 source MCSA : MCSA2 29) chain B residue 403 type catalytic sequence C description 47 source MCSA : MCSA2 30) chain B residue 409 type catalytic sequence R description 47 source MCSA : MCSA2 31) chain B residue 410 type catalytic sequence T description 47 source MCSA : MCSA2 32) chain B residue 403 type ACT_SITE sequence C description Phosphocysteine intermediate source Swiss-Prot : SWS_FT_FI1

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