eF-site ID 1xvp-A PDB Code 1xvp Chain A click to enlarge Title crystal structure of CAR/RXR heterodimer bound with SRC1 peptide, fatty acid and CITCO Classification DNA BINDING PROTEIN Compound Retinoic acid receptor RXR-alpha Source null (NP_003734) Sequence A:  NEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVT NICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWN ELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIF DRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNP AEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALR SIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP Description Functional site 1) chain A residue 272 type sequence A description BINDING SITE FOR RESIDUE F15 A 1002 source : AC2 2) chain A residue 275 type sequence Q description BINDING SITE FOR RESIDUE F15 A 1002 source : AC2 3) chain A residue 313 type sequence F description BINDING SITE FOR RESIDUE F15 A 1002 source : AC2 4) chain A residue 316 type sequence R description BINDING SITE FOR RESIDUE F15 A 1002 source : AC2 5) chain A residue 327 type sequence A description BINDING SITE FOR RESIDUE F15 A 1002 source : AC2 6) chain A residue 345 type sequence I description BINDING SITE FOR RESIDUE F15 A 1002 source : AC2 7) chain A residue 432 type sequence C description BINDING SITE FOR RESIDUE F15 A 1002 source : AC2 8) chain A residue 260 type MOD_RES sequence S description Phosphoserine; by MAPK8 and MAPK9 => ECO:0000250|UniProtKB:P28700 source Swiss-Prot : SWS_FT_FI3 9) chain A residue 327 type BINDING sequence A description BINDING => ECO:0000269|PubMed:16107141, ECO:0000269|PubMed:18800767, ECO:0000269|PubMed:19167885, ECO:0007744|PDB:2ACL, ECO:0007744|PDB:3FAL, ECO:0007744|PDB:3FC6 source Swiss-Prot : SWS_FT_FI1 10) chain A residue 316 type BINDING sequence R description BINDING => ECO:0000269|PubMed:16107141, ECO:0000269|PubMed:18800767, ECO:0000269|PubMed:19167885, ECO:0007744|PDB:2ACL, ECO:0007744|PDB:3FAL, ECO:0007744|PDB:3FC6 source Swiss-Prot : SWS_FT_FI1 11) chain A residue 259 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:24275569 source Swiss-Prot : SWS_FT_FI2

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