eF-site ID 1xrq-A PDB Code 1xrq Chain A click to enlarge Title Crystal structure of active site F1-mutant E245Q soaked with peptide Phe-Leu Classification HYDROLASE Compound Proline iminopeptidase Source null (PIP_THEAC) Sequence A:  ECIENYAKVNGIYIYYKLCKAPEEKAKLMTMHGGPGMSHD YLLSLRDMTKEGITVLFYDQFGCGRSEEPDQSKFTIDYGV EEAEALRSKLFGNEKVFLMGSSYGGALALAYAVKYQDHLK GLIVSGGLSSVPLTVKEMNRLIDELPAKYRDAIKKYGSSG SYENPEYQEAVNYFYHQHLLRSEDWPPEVLKSLEYAERRN VYRIMNGPNEFTITGTIKDWDITDKISAIKIPTLITVGEY DQVTPNVARVIHEKIAGSELHVFRDCSHLTMWEDREGYNK LLSDFILKHL Description Functional site 1) chain A residue 36 type sequence G description BINDING SITE FOR RESIDUE LEU A 301 source : AC1 2) chain A residue 37 type sequence G description BINDING SITE FOR RESIDUE LEU A 301 source : AC1 3) chain A residue 40 type sequence M description BINDING SITE FOR RESIDUE LEU A 301 source : AC1 4) chain A residue 105 type sequence S description BINDING SITE FOR RESIDUE LEU A 301 source : AC1 5) chain A residue 141 type sequence M description BINDING SITE FOR RESIDUE LEU A 301 source : AC1 6) chain A residue 205 type sequence Y description BINDING SITE FOR RESIDUE LEU A 301 source : AC1 7) chain A residue 213 type sequence E description BINDING SITE FOR RESIDUE LEU A 301 source : AC1 8) chain A residue 245 type sequence Q description BINDING SITE FOR RESIDUE LEU A 301 source : AC1 9) chain A residue 271 type sequence H description BINDING SITE FOR RESIDUE LEU A 301 source : AC1 10) chain A residue 244 type ACT_SITE sequence D description ACT_SITE => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 11) chain A residue 105 type ACT_SITE sequence S description Nucleophile source Swiss-Prot : SWS_FT_FI1 12) chain A residue 271 type ACT_SITE sequence H description Proton donor source Swiss-Prot : SWS_FT_FI3

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