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|
eF-site ID
|
1xr0-AB |
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PDB Code
|
1xr0 |
|
Chain
|
A, B |
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click to enlarge
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Title
|
Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors |
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Classification
|
SIGNALING PROTEIN/GROWTH FACTOR RECEPTOR |
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Compound
|
Basic fibroblast growth factor receptor 1 |
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Source
|
Homo sapiens (Human) (FRS2_HUMAN) |
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|
Sequence
|
A: |
HSQMAVHKLAKSIPLRRQVTVS
|
| B: |
MGSDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELIL
YTRKRDSVKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIF
AFKCARAEELFNMLQEIMQNNSINVVEEPVVERNNHQTEL
EVPRTPRTP
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
428 |
| type |
SITE |
| sequence |
T
|
| description |
Breakpoint for translocation to form FGFR1OP2-FGFR1 => ECO:0000269|PubMed:15034873, ECO:0000269|PubMed:16946300, ECO:0000269|PubMed:17389761
|
| source |
Swiss-Prot : SWS_FT_FI1
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