eF-site ID 1xjn-CD PDB Code 1xjn Chain C, D click to enlarge Title Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dATP-CDP complex Classification OXIDOREDUCTASE Compound ribonucleotide reductase, B12-dependent Source null (O33839_THEMA) Sequence C:  MKLSDLISRWIDVEPSKNAQIILRDRYFMKDLDGNYLETK WEDVARRVARVVATAELLNPSYKKNEKLDRIKEWEDIFFR VLKARLFIPNSPTLFNAGLGVKHDLLWKPIDQMTLEDYEE IYRSRNHLHMLSACFVVPVGDSIEEIFEAVKEYALITKVG GGVGSNFSELRPKGSFVAGTHGKASGPVSFMHVFNSAISV VKQGGALMGILNINHPDIEEFIDAKKENVLNFFNLSVGFP MDKKEILKLYEEDGELELSHPRSTIRKKVKIRELFRKIAT NAWKSGDPGLAFLGEMNKYYPLYPHRKINSTNPCGEIGLS DYEACNLGSIDVAKFYNNGFVDLEALQELVQIAVRFLDNV IDVNVFPIDKITKAVKESRRLGLGIMGFADLLYKLEIPYN SQEARDFAANLMAFIALHAHRTSYELGKEKGNFPLLEISR YRTEDNFVPFAMGMSNYDDEIREVMKMTKEFRRNVALLTI APTGSISNIADTSSGLEPNFLLAYTREPLLYVNQVLREKL NPEILKRIEKELIEKGSLKDIPDVPEKIKKVFVVALDIDP MDHLLMQDAFQRYVDNNISKTINMPQSATVDDVLNVYLEA LRTNVRGITVYRDGS D:  MKLSDLISRWIDVEPSKNAQIILRDRYFMKDLDGNYLETK WEDVARRVARVVATAELLNPSYKKNEKLDRIKEWEDIFFR VLKARLFIPNSPTLFNAGLGVKHDLLWKPIDQMTLEDYEE IYRSRNHLHMLSACFVVPVGDSIEEIFEAVKEYALITKVG GGVGSNFSELRPKGSFVAGTHGKASGPVSFMHVFNSAISV VKALMGILNINHPDIEEFIDAKKVLNFFNLSVGFPMDKKE ILKLYEEDGELELSHPRSTIRKKVKIRELFRKIATNAWKS GDPGLAFLGEMNKYYPLYPHRKINSTNPCGEIGLSDYEAC NLGSIDVAKFYNNGFVDLEALQELVQIAVRFLDNVIDVNV FPIDKITKAVKESRRLGLGIMGFADLLYKLEIPYNSQEAR DFAANLMAFIALHAHRTSYELGKEKGNFPLLEISRYRTED NFVPFAMGMSNYDDEIREVMKMTKEFRRNVALLTIAPTGS ISNIADTSSGLEPNFLLAYTRFPLLYVNQVLREKLNPEIL EKELIEKGSLKDIPDVPEKIKKVFVVALDIDPMDHLLMQD AFQRYVDNNISKTINMPQSATVDDVLNVYLEALRTNVRGI TVYRDGS Description Functional site 1) chain D residue 90 type sequence N description BINDING SITE FOR RESIDUE CDP D 1003 source : AC4 2) chain D residue 91 type sequence S description BINDING SITE FOR RESIDUE CDP D 1003 source : AC4 3) chain D residue 133 type sequence A description BINDING SITE FOR RESIDUE CDP D 1003 source : AC4 4) chain D residue 162 type sequence G description BINDING SITE FOR RESIDUE CDP D 1003 source : AC4 5) chain D residue 320 type sequence N description BINDING SITE FOR RESIDUE CDP D 1003 source : AC4 6) chain D residue 321 type sequence P description BINDING SITE FOR RESIDUE CDP D 1003 source : AC4 7) chain D residue 322 type sequence C description BINDING SITE FOR RESIDUE CDP D 1003 source : AC4 8) chain D residue 324 type sequence E description BINDING SITE FOR RESIDUE CDP D 1003 source : AC4 9) chain D residue 489 type sequence A description BINDING SITE FOR RESIDUE CDP D 1003 source : AC4 10) chain D residue 490 type sequence P description BINDING SITE FOR RESIDUE CDP D 1003 source : AC4 11) chain D residue 491 type sequence T description BINDING SITE FOR RESIDUE CDP D 1003 source : AC4 12) chain D residue 492 type sequence G description BINDING SITE FOR RESIDUE CDP D 1003 source : AC4 13) chain D residue 493 type sequence S description BINDING SITE FOR RESIDUE CDP D 1003 source : AC4 14) chain D residue 494 type sequence I description BINDING SITE FOR RESIDUE CDP D 1003 source : AC4 15) chain C residue 90 type sequence N description BINDING SITE FOR RESIDUE CDP C 1004 source : AC5 16) chain C residue 91 type sequence S description BINDING SITE FOR RESIDUE CDP C 1004 source : AC5 17) chain C residue 133 type sequence A description BINDING SITE FOR RESIDUE CDP C 1004 source : AC5 18) chain C residue 161 type sequence G description BINDING SITE FOR RESIDUE CDP C 1004 source : AC5 19) chain C residue 162 type sequence G description BINDING SITE FOR RESIDUE CDP C 1004 source : AC5 20) chain C residue 210 type sequence A description BINDING SITE FOR RESIDUE CDP C 1004 source : AC5 21) chain C residue 320 type sequence N description BINDING SITE FOR RESIDUE CDP C 1004 source : AC5 22) chain C residue 321 type sequence P description BINDING SITE FOR RESIDUE CDP C 1004 source : AC5 23) chain C residue 322 type sequence C description BINDING SITE FOR RESIDUE CDP C 1004 source : AC5 24) chain C residue 324 type sequence E description BINDING SITE FOR RESIDUE CDP C 1004 source : AC5 25) chain C residue 489 type sequence A description BINDING SITE FOR RESIDUE CDP C 1004 source : AC5 26) chain C residue 490 type sequence P description BINDING SITE FOR RESIDUE CDP C 1004 source : AC5 27) chain C residue 491 type sequence T description BINDING SITE FOR RESIDUE CDP C 1004 source : AC5 28) chain C residue 492 type sequence G description BINDING SITE FOR RESIDUE CDP C 1004 source : AC5 29) chain C residue 493 type sequence S description BINDING SITE FOR RESIDUE CDP C 1004 source : AC5 30) chain C residue 494 type sequence I description BINDING SITE FOR RESIDUE CDP C 1004 source : AC5 31) chain C residue 141 type sequence D description BINDING SITE FOR RESIDUE DTP C 1007 source : AC8 32) chain C residue 142 type sequence S description BINDING SITE FOR RESIDUE DTP C 1007 source : AC8 33) chain C residue 143 type sequence I description BINDING SITE FOR RESIDUE DTP C 1007 source : AC8 34) chain C residue 146 type sequence I description BINDING SITE FOR RESIDUE DTP C 1007 source : AC8 35) chain C residue 171 type sequence R description BINDING SITE FOR RESIDUE DTP C 1007 source : AC8 36) chain C residue 177 type sequence V description BINDING SITE FOR RESIDUE DTP C 1007 source : AC8 37) chain C residue 183 type sequence K description BINDING SITE FOR RESIDUE DTP C 1007 source : AC8 38) chain C residue 185 type sequence S description BINDING SITE FOR RESIDUE DTP C 1007 source : AC8 39) chain D residue 158 type sequence K description BINDING SITE FOR RESIDUE DTP C 1007 source : AC8 40) chain D residue 200 type sequence V description BINDING SITE FOR RESIDUE DTP C 1007 source : AC8 41) chain D residue 202 type sequence K description BINDING SITE FOR RESIDUE DTP C 1007 source : AC8 42) chain C residue 127 type sequence H description BINDING SITE FOR RESIDUE DTP C 1008 source : AC9 43) chain C residue 158 type sequence K description BINDING SITE FOR RESIDUE DTP C 1008 source : AC9 44) chain C residue 200 type sequence V description BINDING SITE FOR RESIDUE DTP C 1008 source : AC9 45) chain C residue 201 type sequence V description BINDING SITE FOR RESIDUE DTP C 1008 source : AC9 46) chain C residue 202 type sequence K description BINDING SITE FOR RESIDUE DTP C 1008 source : AC9 47) chain C residue 203 type sequence Q description BINDING SITE FOR RESIDUE DTP C 1008 source : AC9 48) chain D residue 141 type sequence D description BINDING SITE FOR RESIDUE DTP C 1008 source : AC9 49) chain D residue 142 type sequence S description BINDING SITE FOR RESIDUE DTP C 1008 source : AC9 50) chain D residue 143 type sequence I description BINDING SITE FOR RESIDUE DTP C 1008 source : AC9 51) chain D residue 171 type sequence R description BINDING SITE FOR RESIDUE DTP C 1008 source : AC9 52) chain D residue 177 type sequence V description BINDING SITE FOR RESIDUE DTP C 1008 source : AC9 53) chain D residue 178 type sequence A description BINDING SITE FOR RESIDUE DTP C 1008 source : AC9 54) chain D residue 183 type sequence K description BINDING SITE FOR RESIDUE DTP C 1008 source : AC9 55) chain D residue 184 type sequence A description BINDING SITE FOR RESIDUE DTP C 1008 source : AC9 56) chain D residue 185 type sequence S description BINDING SITE FOR RESIDUE DTP C 1008 source : AC9

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