eF-site ID 1xje-B PDB Code 1xje Chain B click to enlarge Title Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dTTP-GDP complex Classification OXIDOREDUCTASE Compound ribonucleotide reductase, B12-dependent Source Thermotoga maritima (O33839_THEMA) Sequence B:  MKLSDLISRWIDVEPSKNAQIILRDRYFMKDLDGNYLETK WEDVARRVARVVATAELLNPSYKKNEKLDRIKEWEDIFFR VLKARLFIPNSPTLFNAGLGVKHDLLWKPIDQMTLEDYEE IYRSRNHLHMLSACFVVPVGDSIEEIFEAVKEYALITKVG GGVGSNFSELRPKGSFVAGTHGKASGPVSFMHVFNSAISV VKQGSRRRGALMGILNINHPDIEEFIDAKKVLNFFNLSVG FPMDKKEILKLYEEDGELELSHPRSTIRKKVKIRELFRKI ATNAWKSGDPGLAFLGEMNKYYPLYPHRKINSTNPCGEIG LSDYEACNLGSIDVAKFYNNGFVDLEALQELVQIAVRFLD NVIDVNVFPIDKITKAVKESRRLGLGIMGFADLLYKLEIP YNSQEARDFAANLMAFIALHAHRTSYELGKEKGNFPLLEI SRYRTEDNFVPFAMGMSNYDDEIREVMKMTKEFRRNVALL TIAPTGSISNIADTSSGLEPNFLLAYTRFPLLYVNQVLRE KLNPEILKRIEKELIEKGSLKDIPDVPEKIKKVFVVALDI DPMDHLLMQDAFQRYVDNNISKTINMPQSATVDDVLNVYL EALRTNVRGITVYRDGSL Description Functional site 1) chain B residue 90 type sequence N description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 2) chain B residue 91 type sequence S description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 3) chain B residue 133 type sequence A description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 4) chain B residue 161 type sequence G description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 5) chain B residue 207 type sequence R description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 6) chain B residue 208 type sequence R description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 7) chain B residue 210 type sequence A description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 8) chain B residue 320 type sequence N description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 9) chain B residue 321 type sequence P description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 10) chain B residue 322 type sequence C description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 11) chain B residue 324 type sequence E description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 12) chain B residue 489 type sequence A description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 13) chain B residue 490 type sequence P description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 14) chain B residue 491 type sequence T description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 15) chain B residue 492 type sequence G description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 16) chain B residue 493 type sequence S description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 17) chain B residue 494 type sequence I description BINDING SITE FOR RESIDUE GDP B 1003 source : AC4 18) chain B residue 141 type sequence D description BINDING SITE FOR RESIDUE TTP B 1004 source : AC5 19) chain B residue 142 type sequence S description BINDING SITE FOR RESIDUE TTP B 1004 source : AC5 20) chain B residue 143 type sequence I description BINDING SITE FOR RESIDUE TTP B 1004 source : AC5 21) chain B residue 171 type sequence R description BINDING SITE FOR RESIDUE TTP B 1004 source : AC5 22) chain B residue 177 type sequence V description BINDING SITE FOR RESIDUE TTP B 1004 source : AC5 23) chain B residue 178 type sequence A description BINDING SITE FOR RESIDUE TTP B 1004 source : AC5 24) chain B residue 179 type sequence G description BINDING SITE FOR RESIDUE TTP B 1004 source : AC5 25) chain B residue 184 type sequence A description BINDING SITE FOR RESIDUE TTP B 1004 source : AC5 26) chain B residue 185 type sequence S description BINDING SITE FOR RESIDUE TTP B 1004 source : AC5 27) chain B residue 190 type sequence F description BINDING SITE FOR RESIDUE TTP B 1004 source : AC5 28) chain B residue 158 type sequence K description BINDING SITE FOR RESIDUE TTP A 1005 source : AC6 29) chain B residue 200 type sequence V description BINDING SITE FOR RESIDUE TTP A 1005 source : AC6 30) chain B residue 201 type sequence V description BINDING SITE FOR RESIDUE TTP A 1005 source : AC6 31) chain B residue 202 type sequence K description BINDING SITE FOR RESIDUE TTP A 1005 source : AC6 32) chain B residue 127 type sequence H description BINDING SITE FOR RESIDUE GOL B 1001 source : AC7 33) chain B residue 158 type sequence K description BINDING SITE FOR RESIDUE GOL B 1001 source : AC7

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