eF-site ID 1xje-A PDB Code 1xje Chain A click to enlarge Title Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dTTP-GDP complex Classification OXIDOREDUCTASE Compound ribonucleotide reductase, B12-dependent Source Thermotoga maritima (O33839_THEMA) Sequence A:  MKLSDLISRWIDVEPSKNAQIILRDRYFMKDLDGNYLETK WEDVARRVARVVATAELLNPSYKKNEKLDRIKEWEDIFFR VLKARLFIPNSPTLFNAGLGVKHDLLWKPIDQMTLEDYEE IYRSRNHLHMLSACFVVPVGDSIEEIFEAVKEYALITKVG GGVGSNFSELRPKGSFVAGTHGKASGPVSFMHVFNSAISV VKQGSRRRGALMGILNINHPDIEEFIDAKKVLNFFNLSVG FPMDKKEILKLYEEDGELELSHPRSTIRKKVKIRELFRKI ATNAWKSGDPGLAFLGEMNKYYPLYPHRKINSTNPCGEIG LSDYEACNLGSIDVAKFYNNGFVDLEALQELVQIAVRFLD NVIDVNVFPIDKITKAVKESRRLGLGIMGFADLLYKLEIP YNSQEARDFAANLMAFIALHAHRTSYELGKEKGNFPLLEI SRYRTEDNFVPFAMGMSNYDDEIREVMKMTKEFRRNVALL TIAPTGSISNIADTSSGLEPNFLLAYTRFVTKEDGTKEPL LYVNQVLREKLNPEILKRIEKELIEKGSLKDIPDVPEKIK KVFVVALDIDPMDHLLMQDAFQRYVDNNISKTINMPQSAT VDDVLNVYLEALRTNVRGITVYRDGSL Description Functional site 1) chain A residue 90 type sequence N description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 2) chain A residue 91 type sequence S description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 3) chain A residue 133 type sequence A description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 4) chain A residue 161 type sequence G description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 5) chain A residue 207 type sequence R description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 6) chain A residue 208 type sequence R description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 7) chain A residue 210 type sequence A description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 8) chain A residue 320 type sequence N description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 9) chain A residue 321 type sequence P description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 10) chain A residue 322 type sequence C description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 11) chain A residue 324 type sequence E description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 12) chain A residue 489 type sequence A description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 13) chain A residue 490 type sequence P description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 14) chain A residue 491 type sequence T description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 15) chain A residue 492 type sequence G description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 16) chain A residue 493 type sequence S description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 17) chain A residue 494 type sequence I description BINDING SITE FOR RESIDUE GDP A 1002 source : AC3 18) chain A residue 158 type sequence K description BINDING SITE FOR RESIDUE TTP B 1004 source : AC5 19) chain A residue 200 type sequence V description BINDING SITE FOR RESIDUE TTP B 1004 source : AC5 20) chain A residue 201 type sequence V description BINDING SITE FOR RESIDUE TTP B 1004 source : AC5 21) chain A residue 202 type sequence K description BINDING SITE FOR RESIDUE TTP B 1004 source : AC5 22) chain A residue 141 type sequence D description BINDING SITE FOR RESIDUE TTP A 1005 source : AC6 23) chain A residue 142 type sequence S description BINDING SITE FOR RESIDUE TTP A 1005 source : AC6 24) chain A residue 143 type sequence I description BINDING SITE FOR RESIDUE TTP A 1005 source : AC6 25) chain A residue 171 type sequence R description BINDING SITE FOR RESIDUE TTP A 1005 source : AC6 26) chain A residue 177 type sequence V description BINDING SITE FOR RESIDUE TTP A 1005 source : AC6 27) chain A residue 178 type sequence A description BINDING SITE FOR RESIDUE TTP A 1005 source : AC6 28) chain A residue 179 type sequence G description BINDING SITE FOR RESIDUE TTP A 1005 source : AC6 29) chain A residue 184 type sequence A description BINDING SITE FOR RESIDUE TTP A 1005 source : AC6 30) chain A residue 185 type sequence S description BINDING SITE FOR RESIDUE TTP A 1005 source : AC6 31) chain A residue 190 type sequence F description BINDING SITE FOR RESIDUE TTP A 1005 source : AC6 32) chain A residue 144 type sequence E description BINDING SITE FOR RESIDUE GOL B 1001 source : AC7

Display surface Download Links