|
|
eF-site ID
|
1xgt-ABC |
|
PDB Code
|
1xgt |
|
Chain
|
A, B, C |
|
click to enlarge
|
|
|
Title
|
Structure for antibody HyHEL-63 Y33L mutant complexed with hen egg lysozyme |
|
Classification
|
IMMUNE SYSTEM |
|
Compound
|
antibody kappa light chain |
|
Source
|
(1XGT) |
|
|
Sequence
|
A: |
MDIVLTQSPATLSVTPGDSVSLSCRASQSISNNLHWYQQK
SHESPRLLIKYASQSISGIPSRFSGSGSGTDFTLSINSVE
TEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIFP
PSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGV
LNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHK
TSTSPIVKSFNRNEC
|
| B: |
EVQLQESGPSLVKPSQTLSLTCSVTGDSVTSDLWSWIRKF
PGNKLEYMGYISYSGSTYYHPSLKSRISITRDTSKNQYYL
QLNSVTTEDTATYYCASWGGDVWGAGTTVTVSSAKTTAPS
VYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWNSGSLS
SGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHP
ASSTKVDKKI
|
| C: |
KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNT
QATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPC
SALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDV
QAWIRGCRL
|
|
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Description
|
(1) |
HyHel-63, unknown protein
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
192-198 |
| type |
prosite |
| sequence |
YTCEATH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
|
| source |
prosite : PS00290
|
|
|
2)
|
chain |
C |
| residue |
76-94 |
| type |
prosite |
| sequence |
CNIPCSALLSSDITASVNC
|
| description |
GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC
|
| source |
prosite : PS00128
|
|
|
3)
|
chain |
C |
| residue |
35 |
| type |
catalytic |
| sequence |
E
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
4)
|
chain |
C |
| residue |
46 |
| type |
catalytic |
| sequence |
N
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
5)
|
chain |
C |
| residue |
48 |
| type |
catalytic |
| sequence |
D
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
6)
|
chain |
C |
| residue |
50 |
| type |
catalytic |
| sequence |
S
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
7)
|
chain |
C |
| residue |
52 |
| type |
catalytic |
| sequence |
D
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
8)
|
chain |
C |
| residue |
59 |
| type |
catalytic |
| sequence |
N
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
9)
|
chain |
C |
| residue |
35 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
10)
|
chain |
C |
| residue |
52 |
| type |
ACT_SITE |
| sequence |
D
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
11)
|
chain |
C |
| residue |
101 |
| type |
BINDING |
| sequence |
D
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|