eF-site ID 1x0r-C PDB Code 1x0r Chain C click to enlarge Title Thioredoxin Peroxidase from Aeropyrum pernix K1 Classification OXIDOREDUCTASE Compound Probable peroxiredoxin Source Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) (TDXH_AERPE) Sequence C:  PGSIPLIGERFPEXEVTTDHGVIKLPDHYVSQGKWFVLFS HPADFTPVCTTEFVSFARRYEDFQRLGVDLIGLSVDSVFS HIKWKEWIERHIGVRIPFPIIADPQGTVARRLGLLHAESA THTVRGVFIVDARGVIRTXLYYPXELGRLVDEILRIVKAL KLGDSLKRAVPADWPNNEIIGEGLIVPPPTTEDQARARXE SGQYRSLDWWFCWDTPASRDDVEEARRYLRRAAEKPAKLL YEEA Description Functional site 1) chain C residue 179 type sequence E description BINDING SITE FOR RESIDUE EDO D 2003 source : AC3 2) chain C residue 232 type sequence R description BINDING SITE FOR RESIDUE EDO C 2004 source : AC4 3) chain C residue 235 type sequence E description BINDING SITE FOR RESIDUE EDO C 2004 source : AC4 4) chain C residue 47 type sequence T description BINDING SITE FOR RESIDUE EDO C 2024 source : CC6 5) chain C residue 48 type sequence P description BINDING SITE FOR RESIDUE EDO C 2024 source : CC6 6) chain C residue 49 type sequence V description BINDING SITE FOR RESIDUE EDO C 2024 source : CC6 7) chain C residue 50 type sequence C description BINDING SITE FOR RESIDUE EDO C 2024 source : CC6 8) chain C residue 126 type sequence R description BINDING SITE FOR RESIDUE EDO C 2024 source : CC6 9) chain C residue 145 type sequence X description BINDING SITE FOR RESIDUE EDO C 2024 source : CC6 10) chain C residue 17 type sequence V description BINDING SITE FOR RESIDUE EDO C 2026 source : CC8 11) chain C residue 18 type sequence T description BINDING SITE FOR RESIDUE EDO C 2026 source : CC8 12) chain C residue 102 type sequence I description BINDING SITE FOR RESIDUE EDO C 2026 source : CC8 13) chain C residue 103 type sequence A description BINDING SITE FOR RESIDUE EDO C 2026 source : CC8 14) chain C residue 109 type sequence V description BINDING SITE FOR RESIDUE EDO C 2026 source : CC8 15) chain C residue 84 type sequence K description BINDING SITE FOR RESIDUE EDO A 2029 source : DC2 16) chain C residue 163 type sequence L description BINDING SITE FOR RESIDUE EDO C 2036 source : DC9 17) chain C residue 167 type sequence L description BINDING SITE FOR RESIDUE EDO C 2036 source : DC9 18) chain C residue 218 type sequence A description BINDING SITE FOR RESIDUE EDO C 2036 source : DC9 19) chain C residue 219 type sequence S description BINDING SITE FOR RESIDUE EDO C 2036 source : DC9 20) chain C residue 222 type sequence D description BINDING SITE FOR RESIDUE EDO C 2036 source : DC9 21) chain C residue 21 type sequence H description BINDING SITE FOR RESIDUE EDO C 2064 source : HC1 22) chain C residue 29 type sequence H description BINDING SITE FOR RESIDUE EDO C 2064 source : HC1 23) chain C residue 43 type sequence P description BINDING SITE FOR RESIDUE EDO C 2067 source : HC4 24) chain C residue 47 type sequence T description BINDING SITE FOR RESIDUE EDO C 2067 source : HC4 25) chain C residue 145 type sequence X description BINDING SITE FOR RESIDUE EDO C 2067 source : HC4 26) chain C residue 193 type sequence E description BINDING SITE FOR RESIDUE EDO C 2075 source : IC3 27) chain C residue 196 type sequence A description BINDING SITE FOR RESIDUE EDO C 2075 source : IC3 28) chain C residue 197 type sequence R description BINDING SITE FOR RESIDUE EDO C 2075 source : IC3 29) chain C residue 228 type sequence R description BINDING SITE FOR RESIDUE EDO C 2080 source : IC8 30) chain C residue 231 type sequence R description BINDING SITE FOR RESIDUE EDO C 2080 source : IC8 31) chain C residue 232 type sequence R description BINDING SITE FOR RESIDUE EDO C 2080 source : IC8 32) chain C residue 235 type sequence E description BINDING SITE FOR RESIDUE EDO C 2080 source : IC8 33) chain C residue 236 type sequence K description BINDING SITE FOR RESIDUE EDO C 2081 source : IC9 34) chain C residue 240 type sequence L description BINDING SITE FOR RESIDUE EDO C 2081 source : IC9 35) chain C residue 237 type sequence P description BINDING SITE FOR RESIDUE EDO C 2082 source : JC1 36) chain C residue 238 type sequence A description BINDING SITE FOR RESIDUE EDO C 2082 source : JC1 37) chain C residue 239 type sequence K description BINDING SITE FOR RESIDUE EDO C 2082 source : JC1 38) chain C residue 65 type sequence Q description BINDING SITE FOR RESIDUE EDO C 2083 source : JC2 39) chain C residue 68 type sequence G description BINDING SITE FOR RESIDUE EDO C 2083 source : JC2 40) chain C residue 33 type sequence Q description BINDING SITE FOR RESIDUE EDO C 2084 source : JC3 41) chain C residue 34 type sequence G description BINDING SITE FOR RESIDUE EDO C 2084 source : JC3 42) chain C residue 35 type sequence K description BINDING SITE FOR RESIDUE EDO C 2084 source : JC3 43) chain C residue 181 type sequence I description BINDING SITE FOR RESIDUE EDO C 2085 source : JC4 44) chain C residue 183 type sequence E description BINDING SITE FOR RESIDUE EDO C 2085 source : JC4 45) chain C residue 166 type sequence S description BINDING SITE FOR RESIDUE EDO H 2114 source : MC6 46) chain C residue 15 type sequence X description BINDING SITE FOR RESIDUE EDO C 2117 source : MC9 47) chain C residue 16 type sequence E description BINDING SITE FOR RESIDUE EDO C 2117 source : MC9 48) chain C residue 108 type sequence T description BINDING SITE FOR RESIDUE EDO C 2117 source : MC9 49) chain C residue 109 type sequence V description BINDING SITE FOR RESIDUE EDO C 2117 source : MC9 50) chain C residue 112 type sequence R description BINDING SITE FOR RESIDUE EDO C 2117 source : MC9 51) chain C residue 231 type sequence R description BINDING SITE FOR RESIDUE EDO D 2119 source : NC2 52) chain C residue 88 type sequence W description BINDING SITE FOR RESIDUE EDO C 2126 source : NC9 53) chain C residue 91 type sequence R description BINDING SITE FOR RESIDUE EDO C 2126 source : NC9 54) chain C residue 193 type sequence E description BINDING SITE FOR RESIDUE EDO E 2127 source : OC1 55) chain C residue 197 type sequence R description BINDING SITE FOR RESIDUE EDO E 2127 source : OC1 56) chain C residue 59 type sequence R description BINDING SITE FOR RESIDUE EDO C 2128 source : OC2 57) chain C residue 60 type sequence R description BINDING SITE FOR RESIDUE EDO C 2128 source : OC2 58) chain C residue 232 type sequence R description BINDING SITE FOR RESIDUE EDO C 2128 source : OC2 59) chain C residue 50 type ACT_SITE sequence C description Cysteine sulfenic acid (-SOH) intermediate => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:16214169, ECO:0000269|PubMed:18436649 source Swiss-Prot : SWS_FT_FI1 60) chain C residue 126 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_00401, ECO:0000269|PubMed:19819903 source Swiss-Prot : SWS_FT_FI2

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