|
|
eF-site ID
|
1wrj-A |
|
PDB Code
|
1wrj |
|
Chain
|
A |
|
click to enlarge
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Title
|
Crystal structure of O6-methylguanine methyltransferase from Sulfolobus tokodaii |
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Classification
|
TRANSFERASE |
|
Compound
|
Methylated-DNA--protein-cysteine methyltransferase |
|
Source
|
Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (OGT_SULTO) |
|
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Sequence
|
A: |
MIVYGLYKSPFGPITVAKNEKGFVMLDFCDCAERSSLDND
YFTDFFYKLDLYFEGKKVDLTEPVDFKPFNEFRIRVFKEV
MRIKWGEVRTYKQVADAVKTSPRAVGTALSKNNVLLIIPC
HRVIGEKSLGGYSRGVELKRKLLELEGIDV
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Description
|
(1) |
Methylated-DNA--protein-cysteine methyltransferase (E.C.2.1.1.63)
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
120 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Nucleophile; methyl group acceptor => ECO:0000255|HAMAP-Rule:MF_00772
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
A |
| residue |
118-124 |
| type |
prosite |
| sequence |
IPCHRVI
|
| description |
MGMT Methylated-DNA--protein-cysteine methyltransferase active site. IPCHRVI
|
| source |
prosite : PS00374
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