|
|
eF-site ID
|
1wcm-C |
|
PDB Code
|
1wcm |
|
Chain
|
C |
|
click to enlarge
|
|
|
Title
|
Complete 12-Subunit RNA Polymerase II at 3.8 Angstrom |
|
Classification
|
TRANSCRIPTION |
|
Compound
|
DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT |
|
Source
|
ORGANISM_COMMON: YEAST; ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE; |
|
|
Sequence
|
C: |
EEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIP
TLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEY
SRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVS
NLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKG
IAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWP
QSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQ
VVVRGIDTLQKKVASILLALTQMDQD
|
|
|
Description
|
(1) |
DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SECOND LARGEST SUBUNIT (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II 45 KDA POLYPEPTIDE (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II 32 KDA POLYPEPTIDE (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASES I, II, AND III 27 KDA POLYPEPTIDE (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASES I, II, AND III 23 KDA POLYPEPTIDE (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II 19 KD POLYPEPTIDE (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASES I, II, AND III 14.5 KDA POLYPEPTIDE (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II 14.2 KDA POLYPEPTIDE (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASES I, II AND III 8.3 KDA POLYPEPTIDE (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II 13.6 KDA POLYPEPTIDE (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASES I, II, AND III 7.7 KDA POLYPEPTIDE (E.C.2.7.7.6)
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
86 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN C1269
|
| source |
: AC5
|
|
|
2)
|
chain |
C |
| residue |
88 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN C1269
|
| source |
: AC5
|
|
|
3)
|
chain |
C |
| residue |
91 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN C1269
|
| source |
: AC5
|
|
|
4)
|
chain |
C |
| residue |
92 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN C1269
|
| source |
: AC5
|
|
|
5)
|
chain |
C |
| residue |
95 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN C1269
|
| source |
: AC5
|
|
|
6)
|
chain |
C |
| residue |
31-71 |
| type |
prosite |
| sequence |
NSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLI
P
|
| description |
RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSLRRvmiaeiptlAidsVevetNtTvlaDEfIAhRLGLIP
|
| source |
prosite : PS00446
|
|
|
|