eF-site ID 1wa5-ABC PDB Code 1wa5 Chain A, B, C click to enlarge Title Structure of the Cse1:Imp-alpha:RanGTP complex Classification TRANSPORT PROTEIN Compound GTP-binding nuclear protein Ran Source (CSE1_YEAST) Sequence A:  PQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVE VHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCA IIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDI KDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLAR KLIGDPNLEF B:  KFVPEYRRTNELRRRRDTQQVELRKAKRDEALAKRRNFQE LPQMTQQLNSDDMQEQLSATVKFRQILSQRPPIDVVIQAG VVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVV DADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDY VLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQP DWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQE AIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGN DLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITA GNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNA SSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLD ALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQ QNENDKIYEKAYKIIETYFGEEEDAV C:  MSDLETVAKFLAESVIASTAKTSERNLRQLETQDGFGLTL LHVIASTNLPLSTRLAGALFFKNFIKRKWVDENGNHLLPA NNVELIKKEIVPLMISLPNNLQVQIGEAISSIADSDFPDR WPTLLSDLASRLSNDDMVTNKGVLTVAHSIFKRWRPLFRS DELFLEIKLVLDVFTAPFLNLLKTVDEQITANENNKASLN ILFDVLLVLIKLYYDFNCQDIPEFFEDNIQVGMGIFHKYL SYSNPLLEDPDETEHASVLIKVKSSIQELVQLYTTRYEDV FGPMINEFIQITWNLLTSISNQPKYDILVSKSLSFLTAVT RIPKYFEIFNNESAMNNITEQIILPNVTLREEDVELFEDD PIEYIRRDLEGTDTRRRACTDFLKELKEKNEVLVTNIFLA HMKGFVDQYMSDPSKNWKFKDLYIYLFTALAINGNITNAG VSSTNNLLNVVDFFTKEIAPDLTSNNIPHIILRVDAIKYI YTFRNQLTKAQLIELMPILATFLQTDEYVVYTYAAITIEK ILTIRESNTSPAFIFHKEDISNSTEILLKNLIALILKHGS SPEKLAENEFLMRSIFRVLQTSEDSIQPLFPQLLAQFIEI VTIMAKNPSNPRFTHYTFESIGAILNYTQRQNLPLLVDSM MPTFLTVFSEDIQEFIPYVFQIIAFVVEQSATIPESIKPL AQPLLAPNVWELKGNIPAVTRLLKSFIKTDSSIFPDLVPV LGIFQRLIASKAYEVHGFDLLEHIMLLIDMNRLRPYIKQI AVLLLQRLQNSKTERYVKKLTVFFGLISNKLGSDFLIHFI DEVQDGLFQQIWGNFIITTLPTIGNLLDRKIALIGVLNMV INGQFFQSKYPTLISSTMNSIIETASSIANLKNDYVEEIS TFGSHFSKLVSISEKPFDPLPEIDVNNGVRLYVAEALNKY NAISGNTFLNTILPQLTQENQVKLNQLLVG Description Functional site 1) chain A residue 122 type MOD_RES sequence N description N-acetylmethionine => ECO:0007744|PubMed:22814378 source Swiss-Prot : SWS_FT_FI1 2) chain A residue 150 type MOD_RES sequence S description N-acetylmethionine => ECO:0007744|PubMed:22814378 source Swiss-Prot : SWS_FT_FI1 3) chain A residue 71 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P62826 source Swiss-Prot : SWS_FT_FI10 4) chain A residue 152 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000250|UniProtKB:P62826 source Swiss-Prot : SWS_FT_FI11 5) chain A residue 69 type SITE sequence Q description Essential for GTP hydrolysis => ECO:0000250|UniProtKB:P62826 source Swiss-Prot : SWS_FT_FI4 6) chain A residue 24 type MOD_RES sequence T description Phosphothreonine => ECO:0000250|UniProtKB:P62826 source Swiss-Prot : SWS_FT_FI6 7) chain A residue 37 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P62826 source Swiss-Prot : SWS_FT_FI7 8) chain A residue 60 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P62826 source Swiss-Prot : SWS_FT_FI7 9) chain A residue 99 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P62826 source Swiss-Prot : SWS_FT_FI7 10) chain A residue 134 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P62826 source Swiss-Prot : SWS_FT_FI7 11) chain A residue 71 type MOD_RES sequence K description N6-acetyllysine; alternate => ECO:0000250|UniProtKB:P62826 source Swiss-Prot : SWS_FT_FI8 12) chain A residue 159 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P62827 source Swiss-Prot : SWS_FT_FI9 13) chain A residue 36 type BINDING sequence E description BINDING => ECO:0000269|PubMed:15602554, ECO:0000269|PubMed:15864302, ECO:0000269|PubMed:19965479, ECO:0007744|PDB:1WA5, ECO:0007744|PDB:2BKU, ECO:0007744|PDB:3A6P, ECO:0007744|PDB:3W3Z source Swiss-Prot : SWS_FT_FI2 14) chain A residue 68 type BINDING sequence G description BINDING => ECO:0000269|PubMed:15602554, ECO:0000269|PubMed:15864302, ECO:0000269|PubMed:19965479, ECO:0007744|PDB:1WA5, ECO:0007744|PDB:2BKU, ECO:0007744|PDB:3W3Z source Swiss-Prot : SWS_FT_FI3

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