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eF-site ID
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1w98-B |
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PDB Code
|
1w98 |
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Chain
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B |
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click to enlarge
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Title
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The structural basis of CDK2 activation by cyclin E |
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Classification
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TRANSFERASE |
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Compound
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CELL DIVISION PROTEIN KINASE 2 |
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Source
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Homo sapiens (Human) (CCNE1_HUMAN) |
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Sequence
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B: |
SPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQP
KMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQEN
VVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACS
GDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDL
HEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAAS
ALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETG
SSKLKHFRGVADEDAHNIQTHRDSLDLLDK
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Description
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Functional site
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|
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1)
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chain |
B |
| residue |
130-161 |
| type |
prosite |
| sequence |
RAILLDWLMEVCEVYKLHRETFYLAQDFFDRY
|
| description |
CYCLINS Cyclins signature. RaiLldWLmevcevykLhretFylAQdFFDRY
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| source |
prosite : PS00292
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2)
|
chain |
B |
| residue |
88 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:19369195, ECO:0007744|PubMed:23186163
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| source |
Swiss-Prot : SWS_FT_FI1
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