eF-site ID 1w85-C PDB Code 1w85 Chain C click to enlarge Title The crystal structure of pyruvate dehydrogenase E1 bound to the peripheral subunit binding domain of E2 Classification OXIDOREDUCTASE Compound PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT Source (ODP2_BACST) Sequence C:  TFQFPFAEQLEKVAEQFPTFQILNEEGEVVNEEAMPELSD EQLKELMRRMVYTRILDQRSISLNRQGRLGFYAPTAGQEA SQIASHFALEKEDFILPGYRDVPQIIWHGLPLYQAFLFSR GHFHGNQIPEGVNVLPPQIIIGAQYIQAAGVALGLKMRGK KAVAITYTGDGGTSQGDFYEGINFAGAFKAPAIFVVQNNR FAISTPVEKQTVAKTLAQKAVAAGIPGIQVDGMDPLAVYA AVKAARERAINGEGPTLIETLCFRYGPHTMSGDDPTRYRS KELENEWAKKDPLVRFRKFLEAKGLWSEEEENNVIEQAKE EIKEAIKKADETPKQKVTDLISIMFEELPFNLKEQYEIYK EKESK Description Functional site 1) chain C residue 173 type sequence D description BINDING SITE FOR RESIDUE MG C1368 source : AC4 2) chain C residue 202 type sequence N description BINDING SITE FOR RESIDUE MG C1368 source : AC4 3) chain C residue 204 type sequence F description BINDING SITE FOR RESIDUE MG C1368 source : AC4 4) chain C residue 102 type sequence Y description BINDING SITE FOR RESIDUE TDP C1370 source : BC3 5) chain C residue 103 type sequence R description BINDING SITE FOR RESIDUE TDP C1370 source : BC3 6) chain C residue 142 type sequence I description BINDING SITE FOR RESIDUE TDP C1370 source : BC3 7) chain C residue 143 type sequence I description BINDING SITE FOR RESIDUE TDP C1370 source : BC3 8) chain C residue 144 type sequence I description BINDING SITE FOR RESIDUE TDP C1370 source : BC3 9) chain C residue 172 type sequence G description BINDING SITE FOR RESIDUE TDP C1370 source : BC3 10) chain C residue 173 type sequence D description BINDING SITE FOR RESIDUE TDP C1370 source : BC3 11) chain C residue 174 type sequence G description BINDING SITE FOR RESIDUE TDP C1370 source : BC3 12) chain C residue 175 type sequence G description BINDING SITE FOR RESIDUE TDP C1370 source : BC3 13) chain C residue 178 type sequence Q description BINDING SITE FOR RESIDUE TDP C1370 source : BC3 14) chain C residue 202 type sequence N description BINDING SITE FOR RESIDUE TDP C1370 source : BC3 15) chain C residue 204 type sequence F description BINDING SITE FOR RESIDUE TDP C1370 source : BC3 16) chain C residue 205 type sequence A description BINDING SITE FOR RESIDUE TDP C1370 source : BC3 17) chain C residue 206 type sequence I description BINDING SITE FOR RESIDUE TDP C1370 source : BC3 18) chain C residue 271 type sequence H description BINDING SITE FOR RESIDUE TDP C1370 source : BC3 19) chain C residue 160 type sequence M description BINDING SITE FOR RESIDUE PEG C1369 source : BC7 20) chain C residue 191 type sequence F description BINDING SITE FOR RESIDUE PEG C1369 source : BC7 21) chain C residue 282 type catalytic sequence R description 106 source MCSA : MCSA2

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