eF-site ID 1w1i-D PDB Code 1w1i Chain D click to enlarge Title Crystal structure of dipeptidyl peptidase IV (DPPIV or CD26) in complex with adenosine deaminase Classification HYDROLASE Compound DIPEPTIDYL PEPTIDASE IV Source ORGANISM_COMMON: BOVINE; ORGANISM_SCIENTIFIC: BOS TAURUS; Sequence D:  SRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILV FNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEY NYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWS PVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGI TDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEY SFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSS VTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRR IQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFR PSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFIT KGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSD YTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLP LYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFII LNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTV FRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRL GTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSM VLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPED NLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQ ISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHF IKQCFSLP Description Functional site 1) chain D residue 630 type ACT_SITE sequence S description Proton donor => ECO:0000250|UniProtKB:P03958 source Swiss-Prot : SWS_FT_FI1 2) chain D residue 708 type ACT_SITE sequence D description Proton donor => ECO:0000250|UniProtKB:P03958 source Swiss-Prot : SWS_FT_FI1 3) chain D residue 740 type ACT_SITE sequence H description Proton donor => ECO:0000250|UniProtKB:P03958 source Swiss-Prot : SWS_FT_FI1 4) chain D residue 547 type catalytic sequence Y description 169 source MCSA : MCSA4 5) chain D residue 630 type catalytic sequence S description 169 source MCSA : MCSA4 6) chain D residue 631 type catalytic sequence Y description 169 source MCSA : MCSA4 7) chain D residue 708 type catalytic sequence D description 169 source MCSA : MCSA4 8) chain D residue 740 type catalytic sequence H description 169 source MCSA : MCSA4

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