|
|
eF-site ID
|
1vyw-D |
|
PDB Code
|
1vyw |
|
Chain
|
D |
|
click to enlarge
|
|
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Title
|
Structure of CDK2/Cyclin A with PNU-292137 |
|
Classification
|
TRANSFERASE |
|
Compound
|
CELL DIVISION PROTEIN KINASE 2 |
|
Source
|
(CGA2_HUMAN) |
|
|
Sequence
|
D: |
YHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDW
LVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVG
TAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHL
VLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLG
ELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLI
RKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSK
YHGVSLLNPPETLNL
|
|
|
Description
|
(1) |
CELL DIVISION PROTEIN KINASE 2 (E.C.2.7.1.37), CYCLIN A2
|
|
Functional site
|
|
|
1)
|
chain |
D |
| residue |
410 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE SO4 D 1433
|
| source |
: AC2
|
|
|
2)
|
chain |
D |
| residue |
414 |
| type |
|
| sequence |
K
|
| description |
BINDING SITE FOR RESIDUE SO4 D 1433
|
| source |
: AC2
|
|
|
3)
|
chain |
D |
| residue |
423 |
| type |
|
| sequence |
L
|
| description |
BINDING SITE FOR RESIDUE SO4 D 1433
|
| source |
: AC2
|
|
|
|