|
|
eF-site ID
|
1vrc_1-ABCD |
|
PDB Code
|
1vrc |
|
Model
|
1 |
|
Chain
|
A, B, C, D |
|
click to enlarge
|
|
|
Title
|
Complex of enzyme IIAmannose and the histidine-containing phosphocarrier protein HPr from escherichia coli nmr, restrained regularized mean structure |
|
Classification
|
TRANSFERASE |
|
Compound
|
PTS system, mannose-specific IIAB component |
|
Source
|
Escherichia coli (strain K12) (PTHP_ECOLI) |
|
|
Sequence
|
A: |
TIAIVIGTHGWAAEQLLKTAEMLLGEQENVGWIDFVPGEN
AETLIEKYNAQLAKLDTTKGVLFLVDTWGGSPFNAASRIV
VDKEHYEVIAGVNIPMLVETLMARDDDPSFDELVALAVET
GREGVKALK
|
| B: |
TIAIVIGTHGWAAEQLLKTAEMLLGEQENVGWIDFVPGEN
AETLIEKYNAQLAKLDTTKGVLFLVDTWGGSPFNAASRIV
VDKEHYEVIAGVNIPMLVETLMARDDDPSFDELVALAVET
GREGVKALK
|
| C: |
MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGK
SASAKSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKL
MAELE
|
| D: |
MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGK
SASAKSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKL
MAELE
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
213-220 |
| type |
prosite |
| sequence |
GLHTRPAA
|
| description |
PTS_HPR_HIS PTS HPR domain histidine phosphorylation site signature. GLHTRPAA
|
| source |
prosite : PS00369
|
|
|
2)
|
chain |
C |
| residue |
239-254 |
| type |
prosite |
| sequence |
GKSASAKSLFKLQTLG
|
| description |
PTS_HPR_SER PTS HPR domain serine phosphorylation site signature. GKsASaKSLFKLQtLG
|
| source |
prosite : PS00589
|
|
|
3)
|
chain |
C |
| residue |
215 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Pros-phosphohistidine intermediate => ECO:0000255|PROSITE-ProRule:PRU00681, ECO:0000269|PubMed:2261470
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
D |
| residue |
215 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Pros-phosphohistidine intermediate => ECO:0000255|PROSITE-ProRule:PRU00681, ECO:0000269|PubMed:2261470
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
A |
| residue |
90 |
| type |
SITE |
| sequence |
I
|
| description |
Involved in the phosphoryl transfer between H-10 and H-175 => ECO:0000305|PubMed:8262947
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
6)
|
chain |
B |
| residue |
90 |
| type |
SITE |
| sequence |
I
|
| description |
Involved in the phosphoryl transfer between H-10 and H-175 => ECO:0000305|PubMed:8262947
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
7)
|
chain |
A |
| residue |
11 |
| type |
MOD_RES |
| sequence |
G
|
| description |
Phosphohistidine; by HPr => ECO:0000305|PubMed:2681202, ECO:0000305|PubMed:8262947
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
8)
|
chain |
B |
| residue |
11 |
| type |
MOD_RES |
| sequence |
G
|
| description |
Phosphohistidine; by HPr => ECO:0000305|PubMed:2681202, ECO:0000305|PubMed:8262947
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
9)
|
chain |
A |
| residue |
56 |
| type |
MOD_RES |
| sequence |
L
|
| description |
N6-acetyllysine => ECO:0000269|PubMed:18723842
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
10)
|
chain |
B |
| residue |
56 |
| type |
MOD_RES |
| sequence |
L
|
| description |
N6-acetyllysine => ECO:0000269|PubMed:18723842
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
|