eF-site ID 1uyg-A PDB Code 1uyg Chain A click to enlarge Title Human Hsp90-alpha with 8-(2,5-dimethoxy-benzyl)-2-fluoro-9H-purin-6-ylamine Classification CHAPERONE Compound HEAT SHOCK PROTEIN HSP 90-ALPHA Source Homo sapiens (Human) (HS9A_HUMAN) Sequence A:  EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDA LDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTG IGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFG VGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTD TGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIG YPITLFVEK Description Functional site 1) chain A residue 51 type sequence N description BINDING SITE FOR RESIDUE PU2 A1224 source : AC1 2) chain A residue 55 type sequence A description BINDING SITE FOR RESIDUE PU2 A1224 source : AC1 3) chain A residue 93 type sequence D description BINDING SITE FOR RESIDUE PU2 A1224 source : AC1 4) chain A residue 96 type sequence I description BINDING SITE FOR RESIDUE PU2 A1224 source : AC1 5) chain A residue 97 type sequence G description BINDING SITE FOR RESIDUE PU2 A1224 source : AC1 6) chain A residue 98 type sequence M description BINDING SITE FOR RESIDUE PU2 A1224 source : AC1 7) chain A residue 107 type sequence L description BINDING SITE FOR RESIDUE PU2 A1224 source : AC1 8) chain A residue 138 type sequence F description BINDING SITE FOR RESIDUE PU2 A1224 source : AC1 9) chain A residue 162 type sequence W description BINDING SITE FOR RESIDUE PU2 A1224 source : AC1 10) chain A residue 184 type sequence T description BINDING SITE FOR RESIDUE PU2 A1224 source : AC1 11) chain A residue 51 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI1 12) chain A residue 93 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI1 13) chain A residue 138 type BINDING sequence F description source Swiss-Prot : SWS_FT_FI1 14) chain A residue 112 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 15) chain A residue 38-47 type prosite sequence YSNKEIFLRE description HSP90 Heat shock hsp90 proteins family signature. YsNKEIFLRE source prosite : PS00298 16) chain A residue 58 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P07901 source Swiss-Prot : SWS_FT_FI4 17) chain A residue 84 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P07901 source Swiss-Prot : SWS_FT_FI4

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