|
|
eF-site ID
|
1uvq-ABC |
|
PDB Code
|
1uvq |
|
Chain
|
A, B, C |
|
click to enlarge
|
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Title
|
Crystal structure of HLA-DQ0602 in complex with a hypocretin peptide |
|
Classification
|
IMMUNE SYSTEM |
|
Compound
|
HLA CLASS II HISTOCOMPATIBILITY ANTIGEN |
|
Source
|
(OREX_HUMAN) |
|
|
Sequence
|
A: |
DIVADHVASCGVNLYQFYGPSGQYTHEFDGDEQFYVDLER
KETAWRWPEFSKFGGFDPQGALRNMAVAKHNLNIMIKRYN
STAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVN
ITWLSNGQSVTEGVSETSFLSKSDHSFFKISYLTFLPSAD
EIYDCKVEHWGLDQPLLKHWEP
|
| B: |
SPEDFVFQFKGMCYFTNGTERVRLVTRYIYNREEYARFDS
DVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHN
YEVAFRGILQRRVEPTVTISPSNLLVCSVTDFYPGQIKVR
WFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDV
YTCHVEHPSLQSPITVEWRAQ
|
| C: |
MNLPSTKVSWAAVGGGGSLV
|
|
|
Description
|
(1) |
HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, OREXIN
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
19 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
A |
| residue |
80 |
| type |
CARBOHYD |
| sequence |
Y
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
A |
| residue |
120 |
| type |
CARBOHYD |
| sequence |
V
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
A |
| residue |
164-170 |
| type |
prosite |
| sequence |
YDCKVEH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YDCKVEH
|
| source |
prosite : PS00290
|
|
|
5)
|
chain |
B |
| residue |
171-177 |
| type |
prosite |
| sequence |
YTCHVEH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YDCKVEH
|
| source |
prosite : PS00290
|
|
|
|