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eF-site ID
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1ur9-AB |
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PDB Code
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1ur9 |
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Chain
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A, B |
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click to enlarge
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Title
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Interactions of a family 18 chitinase with the designed inhibitor HM508, and its degradation product, chitobiono-delta-lactone |
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Classification
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HYDROLASE |
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Compound
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CHITINASE B |
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Source
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(Q54276) |
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Sequence
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A: |
TRKAVIGYYFIPTNQINNYTETDTSVVPFPVSNITPAKAK
QLTHINFSFLDINSNLECAWDPATNDAKARDVVNRLTALK
AHNPSLRIMFSIGGWYYSNDLGVSHANYVNAVKTPASRAK
FAQSCVRIMKDYGFDGVDINWEYPQAAEVDGFIAALQEIR
TLLNQQTITDGRQALPYQLTIAGAGGAFFLSRYYSKLAQI
VAPLDYINLMTYDLAGPWEKVTNHQAALFGDAAGPTFYNA
LREANLGWSWEELTRAFPSPFSLTVDAAVQQHLMMEGVPS
AKIVMGVPFYGRAFKGVSGGNGGQYSSHSTPGEDPYPSTD
YWLVGCEECVRDKDPRIASYRQLEQMLQGNYGYQRLWNDK
TKTPYLYHAQNGLFVTYDDAESFKYKAKYIKQQQLGGVMF
WHLGQDNRNGDLLAALDRYFNAADYDDSQLDMGTGLRYTG
VGPGNLPIMTAPAYVPGTTYAQGALVSYQGYVWQTKWGYI
TSAPGSDSAWLKVGRVR
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| B: |
STRKAVIGYYFIPTNQINNYTETDTSVVPFPVSNITPAKA
KQLTHINFSFLDINSNLECAWDPATNDAKARDVVNRLTAL
KAHNPSLRIMFSIGGWYYSNDLGVSHANYVNAVKTPASRA
KFAQSCVRIMKDYGFDGVDINWEYPQAAEVDGFIAALQEI
RTLLNQQTITDGRQALPYQLTIAGAGGAFFLSRYYSKLAQ
IVAPLDYINLMTYDLAGPWEKVTNHQAALFGDAAGPTFYN
ALREANLGWSWEELTRAFPSPFSLTVDAAVQQHLMMEGVP
SAKIVMGVPFYGRAFKGVSGGNGGQYSSHSTPGEDPYPST
DYWLVGCEECVRDKDPRIASYRQLEQMLQGNYGYQRLWND
KTKTPYLYHAQNGLFVTYDDAESFKYKAKYIKQQQLGGVM
FWHLGQDNRNGDLLAALDRYFNAADYDDSQLDMGTGLRYT
GVGPGNLPIMTAPAYVPGTTYAQGALVSYQGYVWQTKWGY
ITSAPGSDSAWLKVGRVR
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Description
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Functional site
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1)
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chain |
A |
| residue |
136-144 |
| type |
prosite |
| sequence |
FDGVDINWE
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| description |
GH18_1 Glycosyl hydrolases family 18 (GH18) active site signature. FDGVDINwE
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| source |
prosite : PS01095
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