|
|
eF-site ID
|
1u7f-A |
|
PDB Code
|
1u7f |
|
Chain
|
A |
|
click to enlarge
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Title
|
Crystal Structure of the phosphorylated Smad3/Smad4 heterotrimeric complex |
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Classification
|
SIGNALING PROTEIN |
|
Compound
|
Mothers against decapentaplegic homolog 3 |
|
Source
|
Homo sapiens (Human) (SMAD4_HUMAN) |
|
|
Sequence
|
A: |
EPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE
RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAEC
LSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQE
FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQ
TVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSXVX
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
422 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by TGFBR1 => ECO:0000250|UniProtKB:Q8BUN5, ECO:0000255|PROSITE-ProRule:PRU00439
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
2)
|
chain |
A |
| residue |
423 |
| type |
MOD_RES |
| sequence |
X
|
| description |
Phosphoserine; by TGFBR1 => ECO:0000250|UniProtKB:Q8BUN5, ECO:0000255|PROSITE-ProRule:PRU00439
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
|