eF-site ID 1u1g-A
PDB Code 1u1g
Chain A

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Title Structure of E. coli uridine phosphorylase complexed to 5-(m-(benzyloxy)benzyl)barbituric acid (BBBA)
Classification TRANSFERASE
Compound Uridine phosphorylase
Source (UDP_ECOLI)
Sequence A:  SDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVK
LASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQ
LGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHF
APLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFY
PGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLL
TMCASQGLRAGMVAGVIVNRTQAETMKQTESHAVKIVVEA
ARRLL
Description


Functional site

1) chain A
residue 49
type
sequence E
description BINDING SITE FOR RESIDUE K A 1002
source : AC2

2) chain A
residue 69
type
sequence I
description BINDING SITE FOR RESIDUE K A 1002
source : AC2

3) chain A
residue 73
type
sequence S
description BINDING SITE FOR RESIDUE K A 1002
source : AC2

4) chain A
residue 94
type
sequence T
description BINDING SITE FOR RESIDUE BBB A 3300
source : AC4

5) chain A
residue 95
type
sequence T
description BINDING SITE FOR RESIDUE BBB A 3300
source : AC4

6) chain A
residue 96
type
sequence G
description BINDING SITE FOR RESIDUE BBB A 3300
source : AC4

7) chain A
residue 162
type
sequence F
description BINDING SITE FOR RESIDUE BBB A 3300
source : AC4

8) chain A
residue 166
type
sequence Q
description BINDING SITE FOR RESIDUE BBB A 3300
source : AC4

9) chain A
residue 168
type
sequence R
description BINDING SITE FOR RESIDUE BBB A 3300
source : AC4

10) chain A
residue 196
type
sequence E
description BINDING SITE FOR RESIDUE BBB A 3300
source : AC4

11) chain A
residue 197
type
sequence M
description BINDING SITE FOR RESIDUE BBB A 3300
source : AC4

12) chain A
residue 7
type
sequence F
description BINDING SITE FOR RESIDUE BBB B 4300
source : AC5

13) chain A
residue 8
type
sequence H
description BINDING SITE FOR RESIDUE BBB B 4300
source : AC5

14) chain A
residue 48
type
sequence R
description BINDING SITE FOR RESIDUE BBB B 4300
source : AC5

15) chain A
residue 9
type catalytic
sequence L
description 787
source MCSA : MCSA1

16) chain A
residue 81
type catalytic
sequence L
description 787
source MCSA : MCSA1

17) chain A
residue 169
type catalytic
sequence Y
description 787
source MCSA : MCSA1

18) chain A
residue 224
type catalytic
sequence T
description 787
source MCSA : MCSA1

19) chain A
residue 66-81
type prosite
sequence STGIGGPSTSIAVEEL
description PNP_UDP_1 Purine and other phosphorylases family 1 signature. StGIGgPStSIaveEL
source prosite : PS01232


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