eF-site ID 1u1f-ABCDEF PDB Code 1u1f Chain A, B, C, D, E, F click to enlarge Title Structure of e. coli uridine phosphorylase complexed to 5-(m-(benzyloxy)benzyl)acyclouridine (BBAU) Classification TRANSFERASE Compound Uridine phosphorylase Source (UDP_ECOLI) Sequence A:  SDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVK LASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQ LGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHF APLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFY PGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLL TMCASQGLRAGMVAGVIVNRTQTMKQTESHAVKIVVEAAR RLL B:  KSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPV KLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELA QLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLH FAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTF YPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATL LTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAV KIVVEAARRLL C:  SDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVK LASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQ LGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHF APLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFY PGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLL TMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVK IVVEAARRLL D:  SDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVK LASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQ LGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHF APLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFY PGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLL TMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVK IVVEAARRLL E:  KSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPV KLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELA QLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLH FAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTF YPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATL LTMCASQGLRAGMVAGVIVNRTQNAETMKQTESHAVKIVV EAARRLL F:  SDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVK LASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQ LGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHF APLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFY PGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLL TMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVK IVVEAARRLL Description Functional site 1) chain A residue 48 type sequence R description BINDING SITE FOR RESIDUE PO4 B 3301 source : AC1 2) chain B residue 26 type sequence G description BINDING SITE FOR RESIDUE PO4 B 3301 source : AC1 3) chain B residue 30 type sequence R description BINDING SITE FOR RESIDUE PO4 B 3301 source : AC1 4) chain B residue 91 type sequence R description BINDING SITE FOR RESIDUE PO4 B 3301 source : AC1 5) chain B residue 92 type sequence I description BINDING SITE FOR RESIDUE PO4 B 3301 source : AC1 6) chain B residue 93 type sequence G description BINDING SITE FOR RESIDUE PO4 B 3301 source : AC1 7) chain B residue 94 type sequence T description BINDING SITE FOR RESIDUE PO4 B 3301 source : AC1 8) chain B residue 198 type sequence E description BINDING SITE FOR RESIDUE PO4 B 3301 source : AC1 9) chain A residue 26 type sequence G description BINDING SITE FOR RESIDUE PO4 A 4301 source : AC2 10) chain A residue 30 type sequence R description BINDING SITE FOR RESIDUE PO4 A 4301 source : AC2 11) chain A residue 91 type sequence R description BINDING SITE FOR RESIDUE PO4 A 4301 source : AC2 12) chain A residue 92 type sequence I description BINDING SITE FOR RESIDUE PO4 A 4301 source : AC2 13) chain A residue 93 type sequence G description BINDING SITE FOR RESIDUE PO4 A 4301 source : AC2 14) chain A residue 94 type sequence T description BINDING SITE FOR RESIDUE PO4 A 4301 source : AC2 15) chain A residue 198 type sequence E description BINDING SITE FOR RESIDUE PO4 A 4301 source : AC2 16) chain B residue 48 type sequence R description BINDING SITE FOR RESIDUE PO4 A 4301 source : AC2 17) chain C residue 48 type sequence R description BINDING SITE FOR RESIDUE PO4 D 5301 source : AC3 18) chain D residue 26 type sequence G description BINDING SITE FOR RESIDUE PO4 D 5301 source : AC3 19) chain D residue 30 type sequence R description BINDING SITE FOR RESIDUE PO4 D 5301 source : AC3 20) chain D residue 91 type sequence R description BINDING SITE FOR RESIDUE PO4 D 5301 source : AC3 21) chain D residue 92 type sequence I description BINDING SITE FOR RESIDUE PO4 D 5301 source : AC3 22) chain D residue 93 type sequence G description BINDING SITE FOR RESIDUE PO4 D 5301 source : AC3 23) chain D residue 94 type sequence T description BINDING SITE FOR RESIDUE PO4 D 5301 source : AC3 24) chain D residue 198 type sequence E description BINDING SITE FOR RESIDUE PO4 D 5301 source : AC3 25) chain C residue 26 type sequence G description BINDING SITE FOR RESIDUE PO4 C 6301 source : AC4 26) chain C residue 30 type sequence R description BINDING SITE FOR RESIDUE PO4 C 6301 source : AC4 27) chain C residue 91 type sequence R description BINDING SITE FOR RESIDUE PO4 C 6301 source : AC4 28) chain C residue 92 type sequence I description BINDING SITE FOR RESIDUE PO4 C 6301 source : AC4 29) chain C residue 93 type sequence G description BINDING SITE FOR RESIDUE PO4 C 6301 source : AC4 30) chain C residue 94 type sequence T description BINDING SITE FOR RESIDUE PO4 C 6301 source : AC4 31) chain C residue 198 type sequence E description BINDING SITE FOR RESIDUE PO4 C 6301 source : AC4 32) chain D residue 48 type sequence R description BINDING SITE FOR RESIDUE PO4 C 6301 source : AC4 33) chain E residue 48 type sequence R description BINDING SITE FOR RESIDUE PO4 F 7301 source : AC5 34) chain F residue 26 type sequence G description BINDING SITE FOR RESIDUE PO4 F 7301 source : AC5 35) chain F residue 30 type sequence R description BINDING SITE FOR RESIDUE PO4 F 7301 source : AC5 36) chain F residue 91 type sequence R description BINDING SITE FOR RESIDUE PO4 F 7301 source : AC5 37) chain F residue 92 type sequence I description BINDING SITE FOR RESIDUE PO4 F 7301 source : AC5 38) chain F residue 93 type sequence G description BINDING SITE FOR RESIDUE PO4 F 7301 source : AC5 39) chain F residue 94 type sequence T description BINDING SITE FOR RESIDUE PO4 F 7301 source : AC5 40) chain F residue 198 type sequence E description BINDING SITE FOR RESIDUE PO4 F 7301 source : AC5 41) chain E residue 26 type sequence G description BINDING SITE FOR RESIDUE PO4 E 8301 source : AC6 42) chain E residue 30 type sequence R description BINDING SITE FOR RESIDUE PO4 E 8301 source : AC6 43) chain E residue 91 type sequence R description BINDING SITE FOR RESIDUE PO4 E 8301 source : AC6 44) chain E residue 92 type sequence I description BINDING SITE FOR RESIDUE PO4 E 8301 source : AC6 45) chain E residue 93 type sequence G description BINDING SITE FOR RESIDUE PO4 E 8301 source : AC6 46) chain E residue 94 type sequence T description BINDING SITE FOR RESIDUE PO4 E 8301 source : AC6 47) chain E residue 198 type sequence E description BINDING SITE FOR RESIDUE PO4 E 8301 source : AC6 48) chain F residue 48 type sequence R description BINDING SITE FOR RESIDUE PO4 E 8301 source : AC6 49) chain C residue 49 type sequence E description BINDING SITE FOR RESIDUE K C 1001 source : AC7 50) chain C residue 69 type sequence I description BINDING SITE FOR RESIDUE K C 1001 source : AC7 51) chain C residue 73 type sequence S description BINDING SITE FOR RESIDUE K C 1001 source : AC7 52) chain D residue 49 type sequence E description BINDING SITE FOR RESIDUE K C 1001 source : AC7 53) chain D residue 69 type sequence I description BINDING SITE FOR RESIDUE K C 1001 source : AC7 54) chain D residue 73 type sequence S description BINDING SITE FOR RESIDUE K C 1001 source : AC7 55) chain A residue 49 type sequence E description BINDING SITE FOR RESIDUE K A 1002 source : AC8 56) chain A residue 69 type sequence I description BINDING SITE FOR RESIDUE K A 1002 source : AC8 57) chain A residue 73 type sequence S description BINDING SITE FOR RESIDUE K A 1002 source : AC8 58) chain B residue 49 type sequence E description BINDING SITE FOR RESIDUE K A 1002 source : AC8 59) chain B residue 69 type sequence I description BINDING SITE FOR RESIDUE K A 1002 source : AC8 60) chain B residue 73 type sequence S description BINDING SITE FOR RESIDUE K A 1002 source : AC8 61) chain E residue 49 type sequence E description BINDING SITE FOR RESIDUE K E 1003 source : AC9 62) chain E residue 69 type sequence I description BINDING SITE FOR RESIDUE K E 1003 source : AC9 63) chain E residue 73 type sequence S description BINDING SITE FOR RESIDUE K E 1003 source : AC9 64) chain F residue 49 type sequence E description BINDING SITE FOR RESIDUE K E 1003 source : AC9 65) chain F residue 69 type sequence I description BINDING SITE FOR RESIDUE K E 1003 source : AC9 66) chain F residue 73 type sequence S description BINDING SITE FOR RESIDUE K E 1003 source : AC9 67) chain A residue 94 type sequence T description BINDING SITE FOR RESIDUE 183 A 3300 source : BC1 68) chain A residue 95 type sequence T description BINDING SITE FOR RESIDUE 183 A 3300 source : BC1 69) chain A residue 96 type sequence G description BINDING SITE FOR RESIDUE 183 A 3300 source : BC1 70) chain A residue 162 type sequence F description BINDING SITE FOR RESIDUE 183 A 3300 source : BC1 71) chain A residue 166 type sequence Q description BINDING SITE FOR RESIDUE 183 A 3300 source : BC1 72) chain A residue 168 type sequence R description BINDING SITE FOR RESIDUE 183 A 3300 source : BC1 73) chain A residue 195 type sequence Y description BINDING SITE FOR RESIDUE 183 A 3300 source : BC1 74) chain A residue 196 type sequence E description BINDING SITE FOR RESIDUE 183 A 3300 source : BC1 75) chain A residue 197 type sequence M description BINDING SITE FOR RESIDUE 183 A 3300 source : BC1 76) chain A residue 220 type sequence I description BINDING SITE FOR RESIDUE 183 A 3300 source : BC1 77) chain A residue 234 type sequence M description BINDING SITE FOR RESIDUE 183 A 3300 source : BC1 78) chain B residue 7 type sequence F description BINDING SITE FOR RESIDUE 183 A 3300 source : BC1 79) chain B residue 8 type sequence H description BINDING SITE FOR RESIDUE 183 A 3300 source : BC1 80) chain A residue 7 type sequence F description BINDING SITE FOR RESIDUE 183 B 4300 source : BC2 81) chain A residue 8 type sequence H description BINDING SITE FOR RESIDUE 183 B 4300 source : BC2 82) chain A residue 48 type sequence R description BINDING SITE FOR RESIDUE 183 B 4300 source : BC2 83) chain B residue 94 type sequence T description BINDING SITE FOR RESIDUE 183 B 4300 source : BC2 84) chain B residue 96 type sequence G description BINDING SITE FOR RESIDUE 183 B 4300 source : BC2 85) chain B residue 162 type sequence F description BINDING SITE FOR RESIDUE 183 B 4300 source : BC2 86) chain B residue 166 type sequence Q description BINDING SITE FOR RESIDUE 183 B 4300 source : BC2 87) chain B residue 168 type sequence R description BINDING SITE FOR RESIDUE 183 B 4300 source : BC2 88) chain B residue 195 type sequence Y description BINDING SITE FOR RESIDUE 183 B 4300 source : BC2 89) chain B residue 196 type sequence E description BINDING SITE FOR RESIDUE 183 B 4300 source : BC2 90) chain B residue 197 type sequence M description BINDING SITE FOR RESIDUE 183 B 4300 source : BC2 91) chain B residue 220 type sequence I description BINDING SITE FOR RESIDUE 183 B 4300 source : BC2 92) chain B residue 227 type sequence E description BINDING SITE FOR RESIDUE 183 B 4300 source : BC2 93) chain C residue 94 type sequence T description BINDING SITE FOR RESIDUE 183 C 5300 source : BC3 94) chain C residue 95 type sequence T description BINDING SITE FOR RESIDUE 183 C 5300 source : BC3 95) chain C residue 96 type sequence G description BINDING SITE FOR RESIDUE 183 C 5300 source : BC3 96) chain C residue 162 type sequence F description BINDING SITE FOR RESIDUE 183 C 5300 source : BC3 97) chain C residue 166 type sequence Q description BINDING SITE FOR RESIDUE 183 C 5300 source : BC3 98) chain C residue 168 type sequence R description BINDING SITE FOR RESIDUE 183 C 5300 source : BC3 99) chain C residue 195 type sequence Y description BINDING SITE FOR RESIDUE 183 C 5300 source : BC3 100) chain C residue 196 type sequence E description BINDING SITE FOR RESIDUE 183 C 5300 source : BC3 101) chain C residue 197 type sequence M description BINDING SITE FOR RESIDUE 183 C 5300 source : BC3 102) chain C residue 220 type sequence I description BINDING SITE FOR RESIDUE 183 C 5300 source : BC3 103) chain C residue 229 type sequence P description BINDING SITE FOR RESIDUE 183 C 5300 source : BC3 104) chain C residue 234 type sequence M description BINDING SITE FOR RESIDUE 183 C 5300 source : BC3 105) chain D residue 7 type sequence F description BINDING SITE FOR RESIDUE 183 C 5300 source : BC3 106) chain D residue 8 type sequence H description BINDING SITE FOR RESIDUE 183 C 5300 source : BC3 107) chain C residue 7 type sequence F description BINDING SITE FOR RESIDUE 183 D 6300 source : BC4 108) chain C residue 8 type sequence H description BINDING SITE FOR RESIDUE 183 D 6300 source : BC4 109) chain D residue 94 type sequence T description BINDING SITE FOR RESIDUE 183 D 6300 source : BC4 110) chain D residue 95 type sequence T description BINDING SITE FOR RESIDUE 183 D 6300 source : BC4 111) chain D residue 96 type sequence G description BINDING SITE FOR RESIDUE 183 D 6300 source : BC4 112) chain D residue 162 type sequence F description BINDING SITE FOR RESIDUE 183 D 6300 source : BC4 113) chain D residue 166 type sequence Q description BINDING SITE FOR RESIDUE 183 D 6300 source : BC4 114) chain D residue 168 type sequence R description BINDING SITE FOR RESIDUE 183 D 6300 source : BC4 115) chain D residue 195 type sequence Y description BINDING SITE FOR RESIDUE 183 D 6300 source : BC4 116) chain D residue 196 type sequence E description BINDING SITE FOR RESIDUE 183 D 6300 source : BC4 117) chain D residue 197 type sequence M description BINDING SITE FOR RESIDUE 183 D 6300 source : BC4 118) chain D residue 220 type sequence I description BINDING SITE FOR RESIDUE 183 D 6300 source : BC4 119) chain D residue 227 type sequence E description BINDING SITE FOR RESIDUE 183 D 6300 source : BC4 120) chain E residue 94 type sequence T description BINDING SITE FOR RESIDUE 183 E 7300 source : BC5 121) chain E residue 95 type sequence T description BINDING SITE FOR RESIDUE 183 E 7300 source : BC5 122) chain E residue 96 type sequence G description BINDING SITE FOR RESIDUE 183 E 7300 source : BC5 123) chain E residue 162 type sequence F description BINDING SITE FOR RESIDUE 183 E 7300 source : BC5 124) chain E residue 166 type sequence Q description BINDING SITE FOR RESIDUE 183 E 7300 source : BC5 125) chain E residue 168 type sequence R description BINDING SITE FOR RESIDUE 183 E 7300 source : BC5 126) chain E residue 195 type sequence Y description BINDING SITE FOR RESIDUE 183 E 7300 source : BC5 127) chain E residue 196 type sequence E description BINDING SITE FOR RESIDUE 183 E 7300 source : BC5 128) chain E residue 197 type sequence M description BINDING SITE FOR RESIDUE 183 E 7300 source : BC5 129) chain E residue 220 type sequence I description BINDING SITE FOR RESIDUE 183 E 7300 source : BC5 130) chain E residue 234 type sequence M description BINDING SITE FOR RESIDUE 183 E 7300 source : BC5 131) chain F residue 7 type sequence F description BINDING SITE FOR RESIDUE 183 E 7300 source : BC5 132) chain F residue 8 type sequence H description BINDING SITE FOR RESIDUE 183 E 7300 source : BC5 133) chain E residue 7 type sequence F description BINDING SITE FOR RESIDUE 183 F 8300 source : BC6 134) chain E residue 8 type sequence H description BINDING SITE FOR RESIDUE 183 F 8300 source : BC6 135) chain F residue 94 type sequence T description BINDING SITE FOR RESIDUE 183 F 8300 source : BC6 136) chain F residue 96 type sequence G description BINDING SITE FOR RESIDUE 183 F 8300 source : BC6 137) chain F residue 162 type sequence F description BINDING SITE FOR RESIDUE 183 F 8300 source : BC6 138) chain F residue 166 type sequence Q description BINDING SITE FOR RESIDUE 183 F 8300 source : BC6 139) chain F residue 168 type sequence R description BINDING SITE FOR RESIDUE 183 F 8300 source : BC6 140) chain F residue 195 type sequence Y description BINDING SITE FOR RESIDUE 183 F 8300 source : BC6 141) chain F residue 196 type sequence E description BINDING SITE FOR RESIDUE 183 F 8300 source : BC6 142) chain F residue 197 type sequence M description BINDING SITE FOR RESIDUE 183 F 8300 source : BC6 143) chain F residue 221 type sequence V description BINDING SITE FOR RESIDUE 183 F 8300 source : BC6 144) chain A residue 9 type catalytic sequence L description 787 source MCSA : MCSA1 145) chain A residue 81 type catalytic sequence L description 787 source MCSA : MCSA1 146) chain A residue 169 type catalytic sequence Y description 787 source MCSA : MCSA1 147) chain A residue 224 type catalytic sequence T description 787 source MCSA : MCSA1 148) chain B residue 9 type catalytic sequence L description 787 source MCSA : MCSA2 149) chain B residue 81 type catalytic sequence L description 787 source MCSA : MCSA2 150) chain B residue 169 type catalytic sequence Y description 787 source MCSA : MCSA2 151) chain B residue 224 type catalytic sequence T description 787 source MCSA : MCSA2 152) chain C residue 9 type catalytic sequence L description 787 source MCSA : MCSA3 153) chain C residue 81 type catalytic sequence L description 787 source MCSA : MCSA3 154) chain C residue 169 type catalytic sequence Y description 787 source MCSA : MCSA3 155) chain C residue 224 type catalytic sequence T description 787 source MCSA : MCSA3 156) chain D residue 9 type catalytic sequence L description 787 source MCSA : MCSA4 157) chain D residue 81 type catalytic sequence L description 787 source MCSA : MCSA4 158) chain D residue 169 type catalytic sequence Y description 787 source MCSA : MCSA4 159) chain D residue 224 type catalytic sequence T description 787 source MCSA : MCSA4 160) chain E residue 9 type catalytic sequence L description 787 source MCSA : MCSA5 161) chain E residue 81 type catalytic sequence L description 787 source MCSA : MCSA5 162) chain E residue 169 type catalytic sequence Y description 787 source MCSA : MCSA5 163) chain E residue 224 type catalytic sequence T description 787 source MCSA : MCSA5 164) chain F residue 9 type catalytic sequence L description 787 source MCSA : MCSA6 165) chain F residue 81 type catalytic sequence L description 787 source MCSA : MCSA6 166) chain F residue 169 type catalytic sequence Y description 787 source MCSA : MCSA6 167) chain F residue 224 type catalytic sequence T description 787 source MCSA : MCSA6 168) chain A residue 66-81 type prosite sequence STGIGGPSTSIAVEEL description PNP_UDP_1 Purine and other phosphorylases family 1 signature. StGIGgPStSIaveEL source prosite : PS01232

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